High resolutional MR images of cochlear nerves and functional PET of temporal lobes in patients with sensory nerve hearing loss.
High resolutional MR images of cochlear nerves and functional PET of temporal lobes in patients with sensory nerve hearing loss.
批准号:
14570837
负责人:
SATO Noriko
金额:
$1.34万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2002
资助国家:
日本
项目状态:
已结题
起止时间:
2002 至 2003
中文摘要
新的磁共振序列,CISS(建设性干扰与稳定状态),提供了高分辨率的图像,以前没有成像。磁共振CISS图像可显示负责听觉系统的尾椎神经。我们用磁共振连续序列扫描(CISS)检查了听觉障碍患者耳蜗神经的解剖学异常。我们检查了不同疾病之间以及治疗前后耳蜗神经的大小是否存在差异。同时在治疗前后用听觉刺激法在正电子CT上测定脑血容量,并比较治疗有效组与无效组脑血容量的差异。采用MR CISS序列(有效层厚0.7mm)进行高分辨三维扫描,对第7、8颅神经进行垂直重建,并对颅神经进行三维重建。 ...更多信息 对神经来说。比较左右侧耳蜗神经的大小。腮腺炎病毒感染者患侧耳蜗神经的大小小于对侧。但面神经和前庭神经是对称的。而对于认为是血流障碍所致的特发性听力损失患者,双侧听力损失无明显差异。治疗采用激素和高氧治疗。治疗后好转的患者双侧颞叶血容量较治疗前增加。治疗无效的患者治疗前后血容量无明显差异,显示了以前未发现的解剖和功能异常,是临床资产。本方法能客观评价听觉障碍的形态学改变,有助于听觉障碍的准确诊断。少
英文摘要
The new MR sequence, CISS (constructive interference with steady state), provide high resolutional images which had not been imaged before. Cochlear nerve that is responsible for auditory system can be demonstrated by MR CISS images. We examined the anatomical abnormalities of cochlear nerve in patients with auditory disturbance using MR CISS images. We examined whether there is any differences of cochlear nerve size among various diseases or between before and after treatment. At the same time, brain blood volume was also estimated on positron CT by auditory stimulations before and after treatment and examined the differences of brain blood volume between two patients' groups of improvement and non-respons by treatment.Patients with unilateral sensory neural hearing loss without neoplasms such as acoustic shwanoma were selected. High-resolutional 3D images were scanned with MR CISS sequences (effective slice thickness was 0.7mm), and cranial nerve 7th and 8th were reconstructed vertic … More al to the nerves. The size of cochlear nerve on reconstructed images was compared of right and left. In patients who was infetected by mumpus virus, the size of cochlear nerve at disease side was smaller then the contralateral side. But facial and vestibular nerves were symmetric. On the other hand, in patients with idiopathic hearing loss, which are supposed to be caused by blood flow disturbance, there were no differences of both sides.Pure sound stimulation test was examined in patients with idiopathic auditory disturbance on positron CT. The treatment was steroid and high oxygen therapy. In patients who were improved after treatment, bilateral temporal blood volume were increased compared to that before treatment. There were no blood volume differences between before and after treatment in patients who did not respond by the therapy.It is clinical asset to demonstrate anatomical and functional abnormalities that had not been detected before. We evaluate the morphological change objectively and this method is helpful to precise diagnose in patients with auditory disturbance. Less
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