Research on emotional monitoring in children with severe motor and intellectual disabilities

患有严重运动和智力障碍的儿童在表达情绪方面有困难；因此，情绪变化主要是根据他们周围人的经验和观察来主观评估的。在这项研究中，通过量化唾液消化酶α-淀粉酶的水平来评估严重运动和智力残疾儿童的情绪变化。这项研究旨在澄清以下两点：1)唾液淀粉酶与医疗程序造成的痛苦的关系及其意义；2)唾液淀粉酶作为评估严重运动和智力残疾儿童教育和治疗效果的参数的可能性。结果表明，在患有严重运动和智力残疾的儿童中，唾液淀粉酶的活性强烈地反映了医疗程序造成的痛苦程度。此外，唾液淀粉酶…的活性更多的人明显受到交感神经系统活动的影响。Snoezelen是旨在放松患有严重运动和智力障碍的儿童的治疗方法之一，对正常应激(舒适压力)的客观评估证明，唾液淀粉酶的活性反映了正常应激的水平。最后，对严重运动和智力障碍儿童的教育干预措施的效果进行了评估，这些儿童的情绪变化和身体运动由于极度严重的残疾而难以评估，教育干预导致唾液淀粉酶活性的实时显著变化。本研究结果表明，唾液淀粉酶可能是评估严重运动和智力障碍儿童心理状况的有用生物标志物。此外，便携式测试纸条唾液淀粉酶活性监测仪是评估严重运动和智力残疾儿童心理状况的一项优越技术。本研究的结果已在两篇英文论文和两篇日文论文以及九个国内和一个海外学术会议上发表。这些发现表明，唾液淀粉酶分析在对严重运动和智力残疾儿童的研究中是有用的，应该有助于改善他们的生活质量。较少

Children with severe motor and intellectual disabilities have a difficult time expressing emotions; therefore, emotional changes are predominantly assessed subjectively, based on the experiences and observations of people around them. In the present study, the emotional changes in children with severe motor and intellectual disabilities were assessed by quantifying levels of alpha-amylase, a salivary digestive enzyme. The study was designed to clarify the following two points: 1) the relationship of salivary amylase to distress caused by medical procedures, and its significance; and 2) the possibility of using salivary amylase as a parameter for assessing the effects of education and therapy in children with severe motor and intellectual disabilities. The results showed that among children with severe motor and intellectual disabilities the activity of salivary amylase strongly reflected the degree of distress caused by medical procedures. Furthermore, the activity of salivary amylase … More was markedly affected by the activity of the sympathetic nervous system. Snoezelen is one of the treatments that aim to relax children with severe motor and intellectual disabilities, and objective assessments of eustress (comfortable stress) proved that the activity of salivary amylase reflected the level of eustress. Lastly, the effects of educational interventional measures were assessed in children with grave motor and intellectual disabilities in whom emotional changes and body movements are difficult to assess due to extremely severe disabilities, and educational interventions caused significant real time changes in the activity of salivary amylase.The results of the present study suggest that salivary amylase may be a useful biomarker for estimating the psychological status of children with severe motor and intellectual disabilities. In addition, the portable test strip salivary amylase activity monitor was a superior technique for assessing the psychological status of children with severe motor and intellectual disabilities. The results of the present study have been reported in two English papers and two Japanese papers and at nine domestic and one overseas academic conventions. These findings suggest that salivary amylase analysis is useful in research on children with severe motor and intellectual disabilities and should contribute to improving their QOL. Less