Clarification for the central regulation of physical fatigue

通过脑磁图(MEG)、心电图仪(ECG)和心理行为学技术，研究了健康受试者调节体力疲劳的中枢机制。通过使用Ramachandran镜像盒，我们确定了抑制系统的行为和神经证据，以限制身体疲劳期间对侧感觉运动区的激活。此外，前额叶区域被证明是与增强双侧敏感运动区的补偿机制相关的大脑区域。因此，我们为全面了解中枢调节体力疲劳的机制提供了宝贵线索。

The central mechanisms to regulate physical fatigue were examined using magnetoencephalographic (MEG), electrocardiographic (ECG), and psycho-behavioral techniques in healthy participants. By using Ramachandran's mirror box, we identified behavioral and neural evidence of an inhibitory system to limit the activation of the contralateral sensorimotor area during physical fatigue. In addition, the prefrontal area was shown to be a brain region associated with the compensation mechanisms to enhance the bilateral sensirimotor areas. Hence, we have obtained precious clues for the comprehensive understanding of the central mechanisms to regulate physical fatigue.