An approach to the diagnosis of sudden cardiac death : Investigation of a detection method for mutations in genes associated with inherited lethal cardiac arrhythmias

在疑似心源性猝死的法医尸检案例中，尸检结果和病理检查显示没有致命疾病的迹象，我们搜索与遗传性致命性心律失常相关的基因突变。发现了一个突变，提示该突变与心源性猝死有关。在疑似致心律失常性右室心肌病(ARVC)的法医尸检病例中，我们搜索了与ARVC相关的基因突变，并发现了一些突变。在法医尸检案例中，基因分析有助于心源性猝死的科学诊断。

In forensic autopsy cases suspected of sudden cardiac death, where autopsy findings and pathological examination revealed no signs of fatal disease, we searched for mutations in genes associated with inherited lethal cardiac arrhythmias. One mutation was found and it was suggested that this mutation was associated with sudden cardiac death. In forensic autopsy cases suspected of arrhythmogenic right ventricular cardiomyopathy(ARVC), we searched for mutations in genes associated with ARVC and some mutations were found. Genetic analysis is scientifically helpful in the diagnosis of sudden cardiac death in forensic autopsy cases.