Development of microdevices for engineering vascularized tissues

本研究的目的是利用微硫化器件制备的均匀直径的细胞微珠，制造出具有层次化结构和血管网络的三维组织。为了形成由多种细胞类型组成的具有层次结构的三维组织，我们研究了珠子大小和细胞类型的分布。此外，我们还研究了在三维组织中引入血管网络的方法。

The purpose of this study is to produce a three-dimensional tissue with hierarchic structures and vascular networks by using the uniform diameter cell beads fabricated using microfulidic devices. In order to form a three-dimensional tissue with a hierarchical structure consisting of multiple cell types, we investigated the distributions of the bead size and the cell types. Furthermore, we have examined the method to introduce vascular networks within the three-dimensional tissues.