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Fundamental and developmental reseaches of polarized ceramic biomaterials to accelerate the tissue regenerations

Fundamental and developmental reseaches of polarized ceramic biomaterials to accelerate the tissue regenerations
极化陶瓷生物材料加速组织再生的基础和发展研究
批准号:
23300178
负责人:
YAMASHITA Kimihiro
金额:
$11.81万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-01 至 2014-03-31

项目摘要

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中文摘要
翻译
我们研究了用于组织再生和临床应用的陶瓷生物材料的基础研究。表面特性分析表明,电极化提高了陶瓷生物材料表面的表面自由能,改善了陶瓷生物材料表面的润湿性。电极化功能化陶瓷生物材料加速了成骨细胞的增殖、黏附和分化等细胞反应以及骨、皮肤和血管的组织反应。这项研究表明,极化陶瓷生物材料在控制材料与组织之间的界面方面具有促进组织再生的功效。
英文摘要
We studied fundamental researches of ceramic biomaterials for tissue regeneration and clinical applications. The surface characteristics showed that the electrical polarization increased the surface free energy and improved wettability of ceramic biomaterial's surfaces. The functionalized ceramic biomaterials by electrical polarization accelerated the cellular responses such as proliferation, adhesion and differentiation of osteogenic cells and tissue responses of bone, skin and blood vessels. This study showed the efficacy of polarized ceramic biomaterials to enhance the tissue regenerations for control of the interface between materials and tissues.
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DOI: 10.4028/www.scientific.net/kem.529-530.357
发表时间: 2012-11
期刊: Key Engineering Materials
影响因子: --
作者: [Miho Nakamura;A. Nagai;K. Yamashita]
通讯作者: Miho Nakamura;A. Nagai;K. Yamashita
DOI: 10.3109/09513590.2012.683064
发表时间: 2012-10
期刊: Gynecological Endocrinology
影响因子: 2
作者: [Y. Iwahara;A. Nagai;N. Yoshiki;Kaori Igarashi;K. Yamashita;T. Kubota]
通讯作者: Y. Iwahara;A. Nagai;N. Yoshiki;Kaori Igarashi;K. Yamashita;T. Kubota
Improvement of Osteoblast Adhesion through Polarization of Plasma-Sprayed Hydroxyapatite Coatings on Metal
通过金属上等离子喷涂羟基磷灰石涂层的极化提高成骨细胞粘附力
DOI: 10.5405/jmbe.1450
发表时间: 2014
期刊: J. Med. Biol. Eng.
影响因子: --
作者: [M. Nakamura, A. Kobayashi, K. Nozaki, N. Horiuchi, A. Nagai, K. Yamashita]
通讯作者: K. Yamashita
Electric poling of cement composites of hydroxyapatite whiskers with chitosan and their chemical properties in simulated body fluid
羟基磷灰石晶须与壳聚糖水泥复合材料的电极化及其在模拟体液中的化学性能
DOI: 10.2109/jcersj2.121.895
发表时间: 2013
期刊: Journal of the Ceramic Society of Japan
影响因子: 1.1
作者: [M. Nakamura, T. Toyama, A. Morita, N. Horiuchi, K. Nozaki, A. Nagai, K. Yamashita]
通讯作者: K. Yamashita
共 182 条
    エストロゲン活性を有する内分泌撹乱化学物質類の学習記憶能に及ぼす影響評価
    • 批准号:
      22510069
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2010
    • 负责人:
      YAMASHITA Kimihiro
    • 依托单位:
    Efficient induction and maintenance in vivo of tumor antigen specificCD4+ T cells in cancer immunotherapy
    • 批准号:
      22591487
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.41万
    • 财政年份:
      2010
    • 负责人:
      YAMASHITA Kimihiro
    • 依托单位:
    Effects of environmental endocrine disrupters on learning, memory and emotional behavior in the function of central nervous system
    • 批准号:
      12836011
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.62万
    • 财政年份:
      2000
    • 负责人:
      YAMASHITA Kimihiro
    • 依托单位:
    Effects of environmental stresses on the permeability of blood brain barrier
    海外基金