Anthropo-genetics on paleomongoloid in South America

为了明确日本人和安第斯人的古人类关系，本文比较了不同材料中人类t细胞白血病病毒（HTLV）原病毒DNA、线粒体DNA和核DNA的特征：1)南美洲高、低地人；2)安第斯木乃伊；3)日本南部。从HTLV和人类白细胞抗原的DNA分析，明确了安第斯地区的高地人与日本南部有密切的关系，但其他低地的人与他们完全不同。在安第斯地区收集的104具木乃伊中，有两具被鉴定出了人类β -珠蛋白的特定基因。此外，大约1500年前，两具β -珠蛋白阳性的安第斯木乃伊中也有一具HTLV-I pX阳性。对来自智利北部90具木乃伊的线粒体DNA d环区进行的碱基分析已经完成，他们在南美洲的现代人身上发现了四组特定的线粒体DNA。这些结果提供了htlv - 1在殖民时代之前由古代蒙古人携带到安第斯山脉的第一个证据。

To c1arify the paleoanthropological relationship between Japanese and Andeans, characteristics of provirus DNA of human T-cell leukemia virus (HTLV), mitochondrial DNA and nuclear DNA were compared among materials : 1) high and low landers in South America ; 2) Andean mummies ; and 3) southern Japanese. From DNA analysis of HTLV and human leukocyte antigens, it was clarified that high landers in the Andes area were closely related to southern Japanese, but people in other low lands were exclusively different from them. Specific gene human beta-globin was identified from two out of 104 mummies collected in Andes areas. Furthermore, one out two beta-globin positive Andean mummies about 1,500 years ago was positive for HTLV-I pX, too. Base analysis of D-loop regeon of mitochondrial DNA from 90 mummies in north Chile were completed and they showed four specific groups of mitochondrial DNA asshown in contemporary people in South America. These results porvides the first evidence that HTLV-I was carried by ancient Mongoloids to the Andes before the Colonial era. .