Administrative Core

管理核心：摘要 从事阿尔茨海默氏症研究（NEAR）的本地人将被组织成一个行政核心、一个招聘中心 和参与核心，生物标本核心，研究方法核心和3个研究项目。我们还将 将由美国印第安人/阿拉斯加原住民和原住民领导的8个卫星中心组成的全国网络纳入其中 夏威夷/太平洋岛民研究者将协助外展、招募和生物标本采集。 NEAR的主要研究者和行政核心负责人Dedra Buchwald，医学博士， 医学在华盛顿州立大学，是广泛承认她的研究，经验和领导， 原住民社区的阿尔茨海默病和相关痴呆症，以及她为消除健康 差距。她是土著健康伙伴关系的创始主任，这是一个文化上适当的项目。 该研究与15个州的各种土著实体建立了150多个伙伴关系，包括部落， 印第安人的卫生设施，以及为美洲印第安人、阿拉斯加原住民、夏威夷原住民和 太平洋岛民。Buchwald博士将与迈阿密大学教授James Galvin博士一起， 将担任NEAR的科学总监和多个主要研究者，由John Kauwe博士， 他还将担任多个主要研究者和生物标本核心的共同负责人。这一核心 将整合6个学术伙伴机构的贡献，所有这些机构都有与 美洲印第安人/阿拉斯加原住民和夏威夷原住民/太平洋岛民，以及其他代表性不足的少数民族 人口，并在管理，研究方法，奖学金，社区知情的研究， 实地工作和传播。值得注意的是，我们的3个研究项目包括11个部落，7个城市印第安人项目， 一个人工智能拥有的小企业，和5个夏威夷土著服务社区组织。我们的具体目标 1）支持整个学术网站的后勤和实地操作，包括会议的协调， 旅行，并促进与卫星中心的互动; 2）监督管理，组织和 促进、协调、整合和监控跨部门活动和功能的沟通 所有NEAR研究项目，核心，教师和机构; 3）监督和促进关键的实施 战略决策、研究监管流程和数据共享计划; 4）在项目规划方面进行协作， 审查和评价，以确保NEAR实现其目标，并保持其对基于人口的 研究阿尔茨海默病和相关的痴呆症相关的健康差距;和5）召开执行 委员会、外部咨询委员会、出版物和演示委员会、数据安全委员会 和监测委员会，以及社区行动委员会。后者将包括不同的利益相关者和指导 研究当地文化问题和解决方案。总之，行政核心将管理， 协调和监督整个活动范围;监控进度;确保组件计划 实施;并验证所有NEAR支持的研究是否符合联邦法规 和政策NEAR委员会和活动将共同确保所有努力的成功实施。

ADMINISTRATIVE CORE: ABSTRACT Natives Engaged in Alzheimer’s Research (NEAR) will be organized into an Administrative Core, a Recruitment and Engagement Core, a Biospecimen Core, a Research Methods Core, and 3 Research Projects. We will also incorporate a nationwide network of 8 Satellite Centers led by American Indian/Alaska Native and Native Hawaiian/Pacific Islander investigators who will assist with outreach, recruitment, and biospecimen collection. The contact Principal Investigator and Administrative Core Leader of NEAR, Dedra Buchwald, MD, Professor of Medicine at Washington State University, is widely recognized for her research, experience, and leadership in Alzheimer’s disease and related dementias in Native communities, and for her ongoing efforts to eliminate health disparities. She is the Founding Director of Partnerships for Native Health, a program of culturally appropriate research that has established 150+ partnerships with various Native entities in a 15-state region, including tribes, Indian health facilities, and organizations serving American Indians, Alaska Natives, Native Hawaiians, and Pacific islanders. Dr. Buchwald will be joined by James Galvin, MD, MPH, Professor, University of Miami, who will serve as the Scientific Director of NEAR and as a Multiple Principal Investigator and by John Kauwe, PhD, who will also serve as a Multiple Principal Investigator and as Co-Leader of the Biospecimen Core. This Core will integrate the contributions of 6 academic partner institutions, all of which have experience collaborating with American Indian/Alaska Native and Native Hawaiian/Pacific Islander, and other underrepresented minority populations, and with strengths in administration, research methods, scholarship, community-informed research, field work, and dissemination. Notably, our 3 Research Projects include 11 tribes, 7 urban Indian programs, an AI-owned small business, and 5 Native Hawaiian-serving community organizations. Our Specific Aims are to: 1) Support logistical and field operations across academic sites, including coordination of meetings and travel, and facilitate interactions with the Satellite Centers; 2) Oversee a plan for management, organization, and communication that stimulates, coordinates, integrates, and monitors activities and functions across and among all NEAR Research Projects, Cores, faculty, and institutions; 3) Supervise and facilitate implementation of key strategic decisions, research regulatory processes, and data sharing plans; 4) Collaborate on program planning, review, and evaluation to ensure that NEAR achieves its goals and maintains its focus on population-based research in Alzheimer’s disease and related dementias-related health disparities; and 5) Convene the Executive Committee, the External Advisory Committee, the Publications and Presentations Committee, the Data Safety and Monitoring Board, and the Community Action Board. The latter will include diverse stakeholders and guide researchers on local cultural concerns and solutions. In summary, the Administrative Core will manage, coordinate, and supervise the entire range of activities; monitor progress; ensure that component plans are implemented; and verify that all NEAR-supported research is carried out in compliance with Federal regulations and policies. Together, NEAR committees and activities will ensure the successful implementation of all efforts.