Nathan Shock Centers Coordinating Center

内森休克中心协调中心(NSC3)的目标是加强协调和 现有的内森应急中心(NSC)之间的合作，以及加强他们的领导作用和 基础衰老研究中的可见性。国家科学委员会本身的任务是加强对基础设施的研究 老龄化生物学，支持新的研究人员，推动创新，提供资源和智力 在战场上发挥领导作用。成功的NSC3与各个NSC领导团队合作，以 通过共享活动利用各个中心的优势，使所有人受益。《美国人》 老龄化研究联合会(FAR)是一个全国性的非营利性组织，曾是NSC3 自2017年以来。作为协调中心，AFAR提供了一个分享和交流信息的论坛，主要是 通过项目主任会议、国家科学委员会两年一次的会议、年度会议或全国或 国际会议、专门的NSC3网站、网络研讨会和NSC的职业发展活动 试点赠款获得者。NSC3还为NSC提供了一个发挥领导作用的创新机会 在将老龄化研究带入前列的过程中，NIH最近再次强调了加强 通过严谨和透明实现所有生物医学研究的重现性。继续保持远方的优势 作为NSC3包括：(1)建立基础设施，以促进正在进行的NSC3以及新的NSC3 活动；(2)与国家安全委员会和国家安全局领导层关系融洽；(3)建立了对国家安全委员会的综合方法 活动并将国家服务中心和老龄社区与普通公众联系起来；(4)直接接触和 通过以下方式与NIA支持的所有90多个中心及其各自的协调中心进行沟通 研究中心协作网络(RCCN)；(5)远东是一个公正的组织，拥有广泛和 科学界广泛的网络；(6)作为协调中心的示范经验 有许多相似的特点；及(7)由现任和校友组成的完善的受资助人网络，以及 在老龄化研究方面的科学领先地位。FAR将通过以下方式完成NSC3的功能 目标：(1)加强与非专业人士的对外沟通，扩大资源资讯 老龄化及相关领域，并作为国家科学委员会调查人员之间跨地点科学交流的论坛 以及其他由NIA和NIH资助的、联邦和私人资助的促进衰老生物学培训的倡议 和/或研究；(2)与国家安全委员会主任合作，制定、分发和实施共享的 ART方法和对NIH重新强调严谨性、再现性和透明度(RRT)的承诺 在临床前研究中；(3)为NSCs及其与适当的NIA的互动提供后勤支持 工作人员；及(4)制订和实施评估国家服务中心成效的评估策略，以及 NSC3，指导未来方向并向利益攸关方报告结果。

The goal of the Nathan Shock Centers Coordinating Center (NSC3) is to enhance coordination and cooperation among the existing Nathan Shock Centers (NSCs) as well as enhance their leadership role and visibility in basic aging research. The NSCs themselves are tasked with strengthening research in the basic biology of aging, supporting new investigators, driving innovation, providing resources and intellectual leadership to the field. A successful NSC3 works in collaboration with the individual NSC leadership teams to leverage the strengths of the individual centers via shared activities to the benefit of all. The American Federation for Aging Research (AFAR) is a national nonprofit organization which has served as the NSC3 since 2017. As the Coordinating Center, AFAR provides a forum to share and exchange information, primarily through Program Directors meetings, the NSC biannual meeting, annual sessions or symposia at national or international conferences, a dedicated NSC3 website, webinars and career development activities for the NSC pilot grant recipients. The NSC3 also offers an innovative opportunity for the NSCs to assume a leadership role in bringing to the forefront of aging research the newly re-emphasized NIH commitment to enhancing the reproducibility of all biomedical research through rigor and transparency. Advantages of AFAR to continue to serve as the NSC3 include: (1) an established infrastructure to facilitate ongoing as well as new NSC3 activities; (2) a strong rapport with NSC and NIA leadership; (3) an established an integrated approach to NSC activities and linking the NSCs, and aging communities with the lay public; (4) direct access to and communication with all 90+ NIA-supported Centers and their respective Coordinating Centers through the Research Centers Collaborative Network (RCCN); (5) AFAR is an impartial organization with broad and extensive network in the scientific community; (6) a demonstrated experience serving as a Coordinating Center with many similar features; and (7) a well-developed network of grantees, both current and alumni, and scientific leadership in aging research. AFAR will accomplish the functions of the NSC3 through the following aims: (1) Enhance the NSCs external communication with the lay public, expand information on resources in aging and related fields, and serve as a forum of scientific exchange among NSC investigators across sites as well as other NIA- and NIH-funded, federal and privately funded initiatives promoting aging biology training and/or research; (2) Work with the NSC directors to develop, distribute, and implement a shared state-of-the art approach and commitment to the renewed NIH emphasis on rigor, reproducibility and transparency (RRT) in pre-clinical studies; (3) Provide logistical support to the NSCs and their interactions with the appropriate NIA staff; and (4) Develop and implement evaluation strategies for assessing the effectiveness of the NSCs and NSC3, guide future directions and reporting outcomes to stakeholders.