Pilot Projects Program

摘要-试点项目 虽然Advance CTR已经成为改变临床和翻译质量和数量的催化剂， 在罗得岛，仍然需要维持这些成果，并发展以解决 国家的卫生优先事项与社区的参与。此外，我们还发现了新的未得到满足的需求， 调查人员需要促进跨学科网络，加强以社区为基础的研究工作， 并支持对关键初步数据的奖励。这包括为初级调查员提供启动赠款 申请K奖因此，在这次更新申请中，我们的目标是扩大试点项目计划 并在变革性进展的基础上不断发展，以满足调查人员的新需求 社区试点项目计划（PPP）的具体目标是（1）奖励高影响力的试点项目 建议开发预防、诊断和治疗转化方法的项目 （2）促进临床和转化研究， 优先考虑跨学科、机构间和基于社区的合作;（3） 促进初级教员试点项目获奖者的专业发展和校外资助 通过与Advance-CTR核心活动的协同作用;以及（4）加强合作， 罗得岛研究者通过新兴研究领域的交流 研讨会在PPP中，我们将继续征求，审查，奖励，监督和评估为期一年的临床研究。 和转化科学试点项目，从初级研究人员和更高级的研究人员过渡到 一个CTR的焦点。将提供额外的小额赠款，以支持产生关键的初步 数据我们还将通过资助以下机构，促进跨学科和机构间的调查人员网络： 研究务虚会和小额试点赠款，以启动由此产生的新的合作。我们将优先考虑临床 社区参与的研究和项目，解决影响医疗服务不足的疾病 和/或不成比例地影响RI人群的疾病。PPP将继续发挥专业 Advance CTR的其他核心和服务提供的发展机会、功能和设施。在 为了刺激CTR和高影响力领域的合作，PPP将继续举办年度 相关专题研究会。人民党将由Sharon Rounds（核心领导人）领导， 高拉夫·乔杜里它将得到公私伙伴关系指导/审查委员会的支持，其中包括 所有伙伴机构的代表以及社区代表。PPP将继续成为 Advance CTR的组成部分，促进协作和基于社区的临床和转化 研究促进健康。 项目摘要/摘要第607页

ABSTRACT – PILOT PROJECTS PROGRAM While Advance CTR has served as a catalyst to transform the quality and quantity of clinical and translational research (CTR) in Rhode Island, there remains a need to sustain these gains and evolve to address the state’s health priorities with engagement of the community. Furthermore, we have identified new unmet needs of investigators to foster interdisciplinary networks, to enhance community-based research efforts, and to support awards for key preliminary data. This includes jump-start grants for junior investigators applying for K awards. Therefore, in this renewal application, our goal is to expand the Pilot Project Program and build on the transformative progress while evolving to meet the new needs of the investigator community. The Specific Aims of the Pilot Projects Program (PPP) are to (1) award high-impact pilot projects that propose to develop translational approaches for prevention, diagnosis, and treatment of diseases and to improve health in RI; (2) facilitate clinical and translational research through prioritization of interdisciplinary, inter-institutional, and community-based collaborations; (3) promote professional development and extramural funding of junior faculty pilot project awardees through synergy with Advance-CTR Core activities; and (4) strengthen collaboration and communication among Rhode Island investigators through the Emerging Areas of Research Symposium. In the PPP, we will continue to solicit, review, award, oversee, and evaluate one-year clinical and translational science pilot projects from junior investigators and more senior investigators transitioning to a CTR focus. Additional Micro-Grants will be made available to support generation of key preliminary data. We will also promote interdisciplinary and inter-institutional networks of investigators by funding of research retreats and small pilot grants to jump-start resulting new collaborations. We will prioritize clinical and community engaged research and projects that address diseases that affect the medically underserved and/or diseases that disproportionately affect RI population. The PPP will continue to leverage professional development opportunities, functions, and facilities offered by other cores and services of Advance CTR. In order to stimulate CTR and collaboration in high impact areas, the PPP will continue to host an annual research symposium on relevant topics. The PPP will be led by Sharon Rounds (Core Lead) with co-Lead Gaurav Choudhary. It will be supported by the PPP Steering/Review Committee that includes representatives from all partner institutions plus community representatives. The PPP will continue to be an integral part of the Advance CTR, catalyzing collaborative and community-based Clinical and Translational Research to promote health. Project Summary/Abstract Page 607