RNA data development of of cancer cell lines and patients.
RNA data development of of cancer cell lines and patients.
批准号:
10487248
负责人:
William Reinhold
金额:
$6.17万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
Adrenocortical carcinomaAlmanacsAreaCCRCancer cell lineCancerousCell LineCell SurvivalClustered Regularly Interspaced Short Palindromic RepeatsDNA copy numberDataDatabasesDevelopmentDevelopmental Therapeutics ProgramDiseaseEncyclopediasExtramural ActivitiesFutureGeneral HospitalsGenesGeneticGenetic TranscriptionGenomicsGoalsInstitutesKnock-outMalignant NeoplasmsManuscriptsMassachusettsMicroRNAsMolecularNational Cancer InstituteNational Cancer ProgramOncologistOnline SystemsOutputPatientsPatternPharmaceutical PreparationsPharmacologyPhenotypeProtein IsoformsProteinsPublicationsPublishingRNARNA ProcessingRNA SplicingReportingSamplingSiteSourceStandardizationThe Cancer Genome AtlasTissuesTranscriptVariantWorkbioinformatics resourcedrug sensitivitygenetic variantinterestlung small cell carcinomamultiple data sourcesneuroendocrine cancerresponsetool developmenttreatment responseweb app
中文摘要
该项目在转录表达方面特别有用,包括约1,600个细胞系和186名患者的基因水平和在某些情况下的异构体水平。数据的标准化和以网络应用程序的形式呈现,使非生物信息学人员能够访问这些数据。细胞系的工作是在患者之前完成的,因此得到了进一步的发展。患者数据目前驻留在内部站点上。该数据库允许对表型、分子或药理学模式进行多种形式的比较。正在向用户提供数据作为对查询的响应或以TOTO形式提供。细胞系数据可通过我们的CellMiner或CellMinerCDB基于Web的应用程序访问。该项目旨在促进更多的科学分析、工具开发和手稿出版。
英文摘要
This project is particularly informative in the area of transcript expression, including gene and in some cases isoform levels for some 1,600 cell lines and 186 patients. The standardization and presentation of the data in the form of a web-application makes it accessible for non-bioinformatics people. The cell line work was done prior to the patient and thus is further developed. The patient data currently resides on an internal site. The database allows multiple forms of comparisons to phenotypic, molecular, or pharmacological patterns. Data is being provided to the user as response to queries or in toto. The cell line data is accessible through our CellMiner or CellMinerCDB web-based applications. The project is meant to facilitate additional scientific analysis, tool development, and manuscript publication.
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Clustering of the drug activities of the NCI-60 cancerous cell lines
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批准号:8763783
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项目类别:
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资助金额:$6.02万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Comparison of molecular factors to drug activities.
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批准号:8938487
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项目类别:
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资助金额:$8.95万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Genomics and Bioinformatics Group web site development and maintenance.
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批准号:9154337
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项目类别:
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资助金额:$23.25万
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财政年份:--
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负责人:William Reinhold
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依托单位:
RNA sequencing (RNA-Seq) of the NCI-60
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批准号:9780250
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项目类别:
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资助金额:$12.48万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Development of novel molecular or phenotypic databases
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批准号:10262772
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项目类别:
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资助金额:$14.3万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Comparison of molecular factors to drug activities
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批准号:10487249
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项目类别:
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资助金额:$4.94万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Genomics and Systems Pharmacology Core
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批准号:8763780
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项目类别:
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资助金额:$12.04万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Comparative genomic hybridization data and web-based tool for the NCI-60
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批准号:8763782
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项目类别:
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资助金额:$4.51万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Comparison of molecular factors to drug activities
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批准号:10926634
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项目类别:
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资助金额:$12.43万
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财政年份:--
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负责人:William Reinhold
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依托单位:
DNA data development for cancer cell lines and patients
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批准号:10926648
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项目类别:
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资助金额:$9.32万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Comparison of molecular factors to drug activities
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批准号:9556847
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项目类别:
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资助金额:$14.22万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Genomics and Bioinformatics Group web site development and maintenance
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批准号:10262761
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项目类别:
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资助金额:$38.15万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Development of novel molecular or phenotypic databases
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批准号:9344197
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项目类别:
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资助金额:$9.22万
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财政年份:--
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负责人:William Reinhold
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依托单位:
DNA data development for cancer cell lines and patients
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批准号:10487263
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项目类别:
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资助金额:$3.7万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Development of novel molecular or phenotypic databases
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批准号:9556857
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项目类别:
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资助金额:$14.22万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Genomics and Bioinformatics Group web site development and maintenance
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批准号:10703057
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项目类别:
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资助金额:$23.66万
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财政年份:--
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负责人:William Reinhold
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依托单位:
RNA data development of cancer cell lines and patients
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批准号:10703058
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项目类别:
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资助金额:$14.79万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Comparison of molecular factors to drug activities
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批准号:10703059
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项目类别:
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资助金额:$11.83万
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财政年份:--
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负责人:William Reinhold
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依托单位:
Comparison of molecular factors to drug activities
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批准号:9344187
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项目类别:
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资助金额:$12.29万
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财政年份:--
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负责人:William Reinhold
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依托单位:
RNA sequencing (RNA-Seq) of the NCI-60
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批准号:8763781
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项目类别:
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资助金额:$7.52万
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财政年份:--
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负责人:William Reinhold
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依托单位:
海外基金