CORE--ANALYTICAL CHEMISTRY

分析化学核心将在分析化学领域提供支持 计划项目中所有项目的化学领域。这个 此核心的主要职责将是分析提交的样本 由项目调查人员准确、及时地 调查人员可以自信地评估数据，然后再计划 他们的下一阶段调查。要分析的化合物是 维甲醇、维甲酸棕榈酸酯、全反式维甲酸、13-顺式维甲酸 维生素E、β-胡萝卜素、番茄红素、硒、安替比林和 人和动物血浆、皮肤、颊粘膜中的二氟甲基鸟氨酸 细胞、肝脏和皮下脂肪。我们对这些的化验程序 化合物已经得到了很好的证实，并已在同行评议中发表 日记。为了生成准确和一致的数据，核心将 继续执行广泛的质量控制/质量保证计划 我们在保持现有的牢固关系的同时，开发和实施了 与国家标准局合作。核心还将提供 与调查人员协商关于解释 分析数据和/或与分析化学有关的任何事项。在……里面 此外，这一核心将与该领域的当前发展保持同步 为了解决任何特殊的分析问题 核心未来可能会面临。这个岩芯的实验室很好 配备最新的分析仪器和校长 核心调查员和工作人员具有广泛的知识和 有执行上述各项任务的经验。

The Analytical Chemistry Core will provide support in the analytical chemistry area for all projects in the proposed Program Project. The primary responsibility of this Core will be to analyze the sample submitted by the project investigators accurately and timely so that the investigators can evaluate the data with confidence before planning the next phase of their investigations. The compounds to be analyzed are retinol, retinyl-palmitate, all-trans-retinoic acid, 13-cis-retinoic acid, vitamin E, beta-carotene, lycopene, selenium, antipyrine and difluormethylornithine in human and animal plasma, skin, buccal mucosa cells, liver, and subcutaneous fat. Our assay procedures for these compounds are well established and have been published in peer-reviewed journals. In order to generate accurate and consistent data, the Core will continue to follow the extensive quality control/quality assurance program we have developed and carried out while maintaining the existing strong-tie with the National Bureau of Standards. The Core will also provide consultations to the investigators regarding the interpretation of analytical data and/or any matters related to analytical chemistry. In addition, this Core will keep abreast of current developments in the field of analytical chemistry in order to meet any special analytical problems the Core may face in the future. The laboratory of this Core is well equipped with up-to-date analytical instrument and the Principal Investigator and the staff members of the Core have extensive knowledge and experience in carrying out all the tasks mentioned above.