Exploitation of a novel multi-stage electrohydrodynamic device for the manufacture of therapeutic products

多孔颗粒、细气泡和空心胶囊是治疗癌症等疾病的有效药物的重要载体，它们的可靠性和商业上成功的批量生产是一个热门话题。这是因为它直接管理着医学成像和治疗的进展，以推进改善医疗保健的研究前沿。在伦敦大学学院，我们发明了新的多针，多级电驱动设备，可以简单地通过施加电压和流量控制来操作。这些设备已经获得了专利，并获得了2010年创业奖（2.5万英镑），坚固耐用，经济实惠，产品产量高（每分钟几百万）。该产品也可以更好地控制，并且可以制成具有独特结构的隔间，从而具有特殊的治疗效果。这个后续项目的工作将集中在特定的产品和工艺变量上，以便能够大量生产具有特色的可销售产品，并通过将商业计划、营销和许可机会整合在一起来开发其制造。

Porous particles, fine bubbles and hollow capsules are important vehicles for effective agents for the treatment of illnesses such as cancer and their reliable and commercially successful mass production is a hot topic. This is because it directly governs the progress of medical imaging and therapeutics for advancing the frontiers of research for improved healthcare. At UCL we have invented new multi-needle, multi-stage electrically-driven devices which can operate simply using applied voltage and flow rate control. These devices, already patented and the work was awarded the 2010 Venture Prize (£25k), are robust and economical and products are made in high yield (several millions a minute). The products are also better controlled and can be made to have unique structural compartments which allow special therapeutic benefits. The work in this follow-on project will concentrate on specific products and process variables so that characterised marketable products can be made in large quantities and their manufacture exploited by putting together a business plan, marketing and licensing opportunities.