FUNCTIONAL ORGANIZATION OF THE SOMATOSENSORY SYSTEM

六类解剖学和电生理学实验， 提出了关于规范组织、规范发展的建议 组织，以及伤害对正常组织的影响， 猴子躯体感觉系统的发展。 (1)微电极 将使用标测程序和解剖示踪剂来进一步确定 躯体感觉皮层和丘脑的分支， 以及内在联系的区域模式。 (2)单个 单位记录，在某种程度上，多单位记录将被用来 确定神经元中不同的皮质体表征是如何不同的， 响应类型和高密度单个单元“映射”将用于 确定神经元响应类型如何在字段内分布，并且如果 发生神经元响应类型的“模块化”分组。 (3)有限数量 的实验将探索组织和连接的电机和 使用微刺激标测程序的运动前区， 追踪器 (4)实验将开始使用解剖示踪剂， 微电极标测，以研究正常发育的 躯体感觉系统 (5)周围神经损伤的影响，以及 中枢神经系统损害改变正常组织的 成年哺乳动物躯体感觉系统将用微电极进行研究 映射程序。 (6)平行实验将比较对 周围神经损伤与中枢体感系统组织 新生儿和年幼动物的神经系统损伤， 成年人了

Six categories of anatomical and electrophysiological experiments are proposed on the normal organization, the development of normal organization, and the effects of injury on normal organization and development of the somatosensory system of monkeys. (1) Microelectrode mapping procedure and anatomical tracers will be used to determine further subdivisions of the somatosensory cortex and thalamus, the interconnections of subdivisions, and areal patterns of intrinsic connections. (2) Single unit recordings and, to some extent, multi-unit recordings will be used to determine how separate cortical body representations differ in neuron response types, and high density single unit "mapping" will be used to determine how neuron response types are distributed within a field, and if "modular" grouping of neuron response types occurs. (3) A limited number of experiments will explore the organization and connections of motor and premotor fields using microstimulation mapping procedures, and anatomical tracers. (4) Experiments will start using anatomical tracers and microelectrode mapping to investigate the normal development of the somatosensory system. (5) The effects of peripheral nerve injury, and central nervous system damage on altering the normal organization of the somatosensory system in adult mammals will be studied with microelectrode mapping procedures. (6) Parallel experiments will compare the effects on somatosensory system organization of peripheral nerve injury and central nervous system damage in newborn and young animals with those found in adults.