NEURAL CALCULATION IN SENSORIMOTOR CONTROL

将研究人体姿势的感觉运动控制 理论上，与实验研究密切合作， 临床方案。 拟议的研究继续进行中的探索， 简单的方法，神经系统可以控制姿势，通过存储，习惯 响应，使用很少的在线计算。 该提案分为 三大工程： 第一项研究将是由肌肉爆发控制的姿势力学 模式或协同作用。 我们已经描述了 这些协同作用和它们的混合物在准静态的情况下， 尺寸. 本研究将分析扩展到非静态情况， 第三个维度，允许分析应用于更多患者 群体和更自然的情况。 数学方法将允许 一般化到其他运动，例如手臂和头部运动，以及 可以控制的运动轨迹类型的陈述 肌肉爆发模式的类似组合。 第二项研究将描述方位感的协调， 视觉、前庭和触觉，控制运动。 感官 来自三种不同方向感的反馈必须适当地 混合以精确地表示运动。 我们将 研究正常受试者和 前庭患者，以及前庭患者的感觉缺陷如何影响 他们的行动 第三个项目是找到一个联合感觉运动控制的约束条件 一种既能正确解释感官输入， 肌肉力量与身体力学的适当机械相互作用， 支撑面。 本项目将使用前两个项目的成果。

The sensorimotor control of human posture will be investigated theoretically, in close collaboration with experimental studies and clinical programs. The proposed studies continue ongoing explorations of simple ways the nervous system can control posture by stored, habitual responses, using little on-line calculation. This proposal is divided into three major projects: The first study will be on postural mechanics as controlled by muscle burst patterns or synergies. We have described the structure and mechanics of these synergies and their mixtures in the quasi-static case for two dimensions. This study will expand the analysis to non-static cases and to a third dimension, allowing the analysis to be applied to more patient groups and more natural situations. The mathematical approach will allow a generalization to other movements, such as arm and head movements, and a statement of the types of movement trajectories that can be controlled by analogous combinations of muscle burst patterns. The second study will describe the coordination of orientation senses, visual, vestibular, and tactile, in controlling movements. Sensory feedback from the three different orientation senses must be properly blended to give an accurate representation of movement. We will investigate how this is done by both normal subjects and groups of vestibular patients, and how sensory deficits in vestibular patients affect their movements. The third project is to find constraints on a combined sensorimotor control system which allows both proper interpretation of sensory inputs and appropriate mechanical interaction of muscle forces with body mechanics and the support surface. This project will use the results of the previous two.