STATISTICAL ANALYSIS OF PEDIATRIC TASK FORCE DATA BASE

高血压是公认的心血管疾病的危险因素 在成年人身上。此外，许多研究表明，有跟踪 在儿童纵向血压测量中。一个重要的 儿科高血压研究中尚未解决的目标是定义什么是 儿童血压水平是成人患病风险增加的原因 高血压。在血压方面有两个NHLBI工作组 1977年和1987年发表了报告的《儿童的控制》。其中之一 每个特别工作组的目标一直是为以下目标定义适当的百分位数 儿童的血压。在工作队第二份报告中，结果来自 9项大型流行病学研究被合并为一个数据库，其中包含更多 超过70,000个读数，从中得出血压百分位数为 年龄和性别的函数。然而，许多研究人员表示， 身高与血压的关系比年龄更强，并敦促 儿童血压的标准数据应以身高为界 而不是年龄。此应用程序的一个重要目标是定义 性别特定的血压百分位数是年龄和 高度。 高血压研究中另一个悬而未决的问题是定义准确的 不同种族人群血压分布的年龄 分流。这是少数几个可以解决此问题的数据库之一 因为我们有超过43,000名白人儿童，23,000名黑人儿童的读数 儿童，以及4500名西班牙裔儿童。这将是一个非常充足的 样本大小来检验这一假设。如果发现了不同之处，那就是 对估计种族差异的最早年龄非常有意义 对血压的影响是显而易见的。 总而言之，儿科工作队以前的报告仅限于 所列数据的范围，主要是由于篇幅的限制。我们会 构建血压百分位数是年龄、性别、种族、 和身高，这应该提供一个更全面的儿科概况 血压分布比以前发表的任何研究成果都要多。

Hypertension is a well-recognized risk factor for cardiovascular disease in adults. Furthermore, many studies have shown that there is tracking among longitudinal pediatric blood pressure determinations. An important unresolved goal in pediatric hypertension research is to define at what level of pediatric blood pressure is a child at increased risk for adult hypertension. There have been two NHLBI Task Forces in Blood Pressure Control in Children which have published reports in 1977 and 1987. One of the goals of each task force has been to define appropriate percentiles for blood pressure in children. In the Second Task Force Report, results from nine large epidemiologic studies were combined into a data base with more than 70,000 readings from which blood pressure percentiles were derived as a function of age and sex. However, many research workers have stated that height is more strongly related to blood pressure than age and have urged that Normative data for pediatric blood pressure be demarcated by height rather than age. An important goal of this application is to define sex-specific blood pressure percentiles that are a function of both age and height. Another unresolved issue in hypertension research is to define the precise age at which blood pressure distributions for different racial groups diverge. This is one of the few data bases that can address this issue since we have readings from over 43,000 white children, 23,000 black children, and 4,500 hispanic children. This will be a more than adequate sample size to test this hypothesis. If differences are found, than it is of great interest to estimate the earliest age at which racial differences in blood pressure are apparent. In summary, the previous Pediatric Task Force reports have been limited in the scope of data presented, mainly due to space limitations. We will construct blood pressure percentiles that are a function of age, sex, race, and height, which should provide a more comprehensive profile of pediatric blood pressure distributions than any previously published work.