A QUASIMONOCHROMATIC X-RAY SOURCE FOR MAMMOGRAPHY
A QUASIMONOCHROMATIC X-RAY SOURCE FOR MAMMOGRAPHY
批准号:
3493351
负责人:
Melvin Arthur Piestrup
金额:
$5.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-07-01 至 1994-03-31
中文摘要
该计划的目的是调查使用
作为可调准单色X射线的参数X射线辐射(PXR)
乳腺X线摄影的来源。 PXR是通过将天然或合成的
晶体,或多层结构进入相对论的路径,
电子束 与光场相关的虚光子
电子被周期性晶格布拉格反射,并且真实的
X射线以布拉格角出现。 因此,生产过程
类似于晶体的X射线衍射,除了X射线束
以布拉格角入射的电子束被相对论性电子束代替。
这种类激光源是准单色的,定向的,容易
可调谐和可极化。 这样的来源将允许确定
使剂量最小化,
肿瘤和正常乳腺组织之间的对比。 我们建议发展
乳腺X射线摄影的蒙特卡罗模拟,将计算图像
质量和剂量作为光子能量和带宽的函数,
我们的PXR线人 我们将确定乳房X光检查所需的光子通量
可以从PXR源获得。 为了让源头更
实际上,我们将研究减少所需电子的方法。
能量低于20 MeV。 PXR生成的实验确认
在低到中等的电子束能量下,将尝试使用
现有的实验装置。
英文摘要
The objective of the proposed program is to investigate the use of
parametric x-ray radiation (PXR) as a tunable, quasimonochromatic x-ray
source for mammography. PXR is generated by placing natural or synthetic
crystals, or multilayer structures into the path of a relativistic
electron beam. The virtual photons associated with the fields of the
electrons are Bragg reflected by the periodic crystal lattice and real
x-rays appear at the Bragg angle. The production process is thus
analogous to x-ray diffraction by crystals, except that the x-ray beam
incident at the Bragg angle is replaced by a relativistic electron beam.
This laser-like source is quasi-monochromatic, directional, easily
tunable, and polarizable. Such a source would permit the determination
of the optimum photon energy which minimizes dosage and maximizes
contrast between tumors and normal breast tissue. We propose to develop
a Monte Carlo simulation of mammography, which will calculate image
quality and dosage as a function of the photon energy and bandwidth of
our PXR source. We will determine the needed photon flux for mammography
that can be obtained from a PXR source. To make the source more
practical, we will investigate methods for reducing the needed electron
beam energy to below 20 MeV. Experimental confirmation of PXR generation
at low to moderate electron beam energies will be attempted using an
existing experimental setup.
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会议论文
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资助金额:$10.0万
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财政年份:2000
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负责人:Melvin Arthur Piestrup
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依托单位:
HIGH INTENSITY X-RAY SOURCE FOR MEDICAL IMAGING
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批准号:2287146
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资助金额:$9.06万
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财政年份:1996
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负责人:Melvin Arthur Piestrup
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HIGH INTENSITY X RAY SOURCE FOR MEDICAL IMAGING
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批准号:2718042
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资助金额:$46.45万
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财政年份:1996
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HIGH INTENSITY X RAY SOURCE FOR MEDICAL IMAGING
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批准号:6078289
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资助金额:$28.3万
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财政年份:1996
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负责人:Melvin Arthur Piestrup
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依托单位:
A METAL-OXIDE, CHARACTERISTIC-LINE X-RAY IMAGING SOURCE
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资助金额:$5.0万
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财政年份:1988
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负责人:Melvin Arthur Piestrup
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依托单位:
CHANNELING RADIATION FOR NON-INVASIVE ANGIOGRAPHY
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批准号:3508571
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项目类别:
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资助金额:$25.12万
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财政年份:1986
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负责人:Melvin Arthur Piestrup
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依托单位:
CHANNELING RADIATION FOR NON-INVASIVE ANGIOGRAPHY
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批准号:3508572
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项目类别:
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资助金额:$25.0万
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财政年份:1986
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负责人:Melvin Arthur Piestrup
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依托单位:
THE APPLICATION OF CHANNELING RADIATION TO ANGIOGRAPHY
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批准号:3500990
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项目类别:
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资助金额:$5.0万
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财政年份:1986
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负责人:Melvin Arthur Piestrup
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依托单位:
海外基金