FGF RECEPTOR EXPRESSION IN TUMORS

我们分析了肿瘤细胞系的FGF受体表达。 我们的结果 表明FLG-FLG受体和碱性FGF可能参与 横纹肌肉瘤中的自分泌刺激 同样，我们的结果 表明FLG-FGF受体和酸性FGF可能参与了 神经胶质瘤中的自分泌刺激。 表情模式或者这个 受体与第二FGF受体BEK显著不同。 的 这两种受体的作用差异仍不清楚。 最近 有证据表明FLG-FGF受体也是HSV 1受体。 表达模式对于FGF受体研究和 as a means手段of determining确定potentialsites地点of HSV感染.

We analyzed tumor cell lines for FGF receptor expression. Our results indicate that the FLG-FLG receptor and basic FGF may be involved in autocrine stimulation in rhabdomyosarcomas. Similarly, our results indicate that the FLG-FGF receptor and acidic FGF may be involved in autocrine stimulation in glial tumors. The expression pattern or this receptor differs significantly from a second FGF receptor BEK. The difference in the roles of these two receptors remains unclear. Recent evidence indicates that the FLG-FGF receptor is also the HSV 1 receptor. The pattern of expression is a value both for the FGF receptor studies and as a means of determining potentialsites of HSV infection.