FACTORS INFLUENCING GENETIC TRANSCRIPTION-- INITIATION AND TERMINATION

这个项目的目的是检查某些人的参与情况 细胞事件中的核糖核酸酶。这个项目的范围已经发展到 包括蛋白质化学、酶活性、蛋白质过量生产 以及体内酶活性水平变化的后果 牢房。大多数实验方法的基础都是推导出来的 从酶学的角度来看。检查特定对象的能力 从蛋白质的初级氨基酸序列到 体内酶活性水平变化的后果 细胞给了我们机会来研究酶和 这些耐人寻味的酶的功能作用。第二个感兴趣的领域是 在大肠杆菌中进行诱变。

The aim of this project is to examine the involvement of certain ribonucleases in cellular events. The scope of this project has evolved to include protein chemistry, enzymatic activity, overproduction of proteins and the consequences of changes in the level of enzymatic activity within the cell. The basis for most of the experimental approaches is derived from an enzymological perspective. The ability to examine a particular event in great detail from primary amino acid sequence of a protein to the consequences of alteration of the level of enzymatic activity within the cell has given us the opportunity to study both the enzymological and functional roles of these intriguing enzymes. A second area of interest is mutagenesis in E. coli.