DEVELOPMENT OF BIOPHYSICAL METHODS FOR STUDYING BIOCHEMICAL REACTIONS

关于开发各种评估仪器的工作 作为血液替代品的血红蛋白衍生品已经在一个 随着LAIR试点工厂的上线，速度加快 可以提供大量的蛋白质。氧平衡曲线 该仪器目前正在人体血红蛋白样本上进行测试。量热法 一氧化碳、二氧化碳结合力的测定 氯化物转化为HbAo和DBBF-Hb产品正在进行中。在这方面取得的进展 近红外光谱分析技术在三磷酸腺苷、二磷酸腺苷和磷酸盐研究中的应用 他们对ATPase的反应已经发展到了一个单独的 目前正在为这项工作编写进度报告。初始拉曼光谱 已经采取了显示不同的磷酸盐部分的 不同的核苷酸。关于这项工作的另一份报告也在进行中 已提交。

Work on the development of instrumentation for the evaluation of various hemoglobin derivatives proposed as a blood substitute has proceeded at an accelerated rate with the coming on line of the pilot plant at LAIR which can furnish large amounts of the protein. The oxygen equilibrium curve apparatus is now being tested on human hemoglobin samples. Calorimetric measurements of the binding of carbon monoxide, carbon dioxide, & chloride to HbAo and the DBBF-Hb product are underway. Progress on the use of near-infra red spectroscopy for studying ATP,ADP, & phosphate in their reactions with ATPase has proceeded to the point that a separate progress report is being written for this work. Initial Raman spectra have been taken which show differences in the phosphate moiety of the different nucleotides. A separate report on this work is also being submitted.