Defining immune regulation and T cell responses during chronic infectious disease.

艾滋病毒/艾滋病、结核病、疟疾和利什曼病等慢性传染病是造成大量发病率和死亡率的原因。它们的特点都是严重的免疫功能障碍。我们将研究一种寄生虫感染，以确定促进慢性传染病的重要免疫细胞群和分子。这方面的知识将有助于开发更好的治疗方法和疫苗，以治疗影响世界许多地区人民的一系列传染病。

Chronic infectious diseases such as HIV/AIDS, tuberculosis, malaria and leishmaniasis are responsible for significant morbidity and mortality. They are all characterised by severe immune dysfunction. We will study a parasitic infection to identify important immune cell populations and molecules that promote chronic infectious disease. This knowledge will enable the development of better treatments and vaccines for range of infectious diseases that affect people in many parts of the world.