Defining the role of reserve stem cells in gastric cancer
Defining the role of reserve stem cells in gastric cancer
批准号:
nhmrc : GNT1120362
负责人:
A/Pr Daniel Worthley
金额:
$56.37万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
每年有超过80万人死于胃癌。这种通常是致命的疾病是由胃壁慢性炎症引起的。这项提案将研究胃炎如何对一种新型的“癌症干细胞”进行“重新编程”以形成肿瘤,并评估通过治疗来靶向这些细胞以预防疾病的方法。总而言之,这些研究将为胃癌预防和治疗提供新的方法。
英文摘要
Over 800,000 deaths from stomach cancer occur annually. This often fatal disease is caused by chronic inflammation of the stomach lining. This proposal will investigate how stomach inflammation ‘reprograms’ a new type of 'cancer stem cell' to form tumours and evaluate ways to therapeutically target these cells to prevent disease. Collectively, these studies will inform new approaches for stomach cancer prevention and treatment.
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会议论文
Bridging the GAPP between the laboratory and clinic to prevent Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS).
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批准号:nhmrc : GNT1143414
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项目类别:Project Grants
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资助金额:$72.49万
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财政年份:2018
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负责人:A/Pr Daniel Worthley
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依托单位:
Bridging the GAPP between the laboratory and clinic to prevent Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS).
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批准号:nhmrc : 1143414
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项目类别:Project Grants
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资助金额:$49.01万
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财政年份:2018
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负责人:A/Pr Daniel Worthley
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依托单位:
Defining the role of reserve stem cells in gastric cancer
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批准号:nhmrc : 1120362
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项目类别:Project Grants
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资助金额:$38.47万
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财政年份:2017
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负责人:A/Pr Daniel Worthley
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依托单位:
Why is the bone marrow a “hot-spot” for myeloma plasma cell metastasis: are there Gremlins in the system?
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批准号:nhmrc : GNT1104031
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项目类别:Project Grants
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资助金额:$65.2万
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财政年份:2016
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负责人:A/Pr Daniel Worthley
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依托单位:
Why is the bone marrow a “hot-spot” for myeloma plasma cell metastasis: are there Gremlins in the system?
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批准号:nhmrc : 1104031
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项目类别:Project Grants
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Osteochondroreticular stem cell therapy for osteoarthritis: the right cells for the job.
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批准号:nhmrc : 1099283
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项目类别:Project Grants
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资助金额:$38.51万
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财政年份:2016
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负责人:A/Pr Daniel Worthley
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依托单位:
Eradicating preventable deaths from colorectal cancer - the Beat Bowel Cancer Project.
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批准号:nhmrc : 1133042
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项目类别:Partnerships
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资助金额:$6.74万
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财政年份:2016
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负责人:A/Pr Daniel Worthley
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依托单位:
Using connective tissue stem cells to treat human disease.
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批准号:nhmrc : GNT1110941
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项目类别:Career Development Fellowships
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资助金额:$41.92万
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财政年份:2016
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负责人:A/Pr Daniel Worthley
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依托单位:
Osteochondroreticular stem cell therapy for osteoarthritis: the right cells for the job.
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批准号:nhmrc : GNT1099283
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项目类别:Project Grants
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资助金额:$56.2万
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财政年份:2016
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负责人:A/Pr Daniel Worthley
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依托单位:
Using connective tissue stem cells to treat human disease.
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批准号:nhmrc : 1110941
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项目类别:Career Development Fellowships
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资助金额:$28.84万
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财政年份:2016
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负责人:A/Pr Daniel Worthley
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依托单位:
Gastrointestinal mesenchyme supports intestinal stem cells, promotes intestinal regeneration and drives cancer.
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批准号:nhmrc : 1081852
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项目类别:Project Grants
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资助金额:$36.58万
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财政年份:2015
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负责人:A/Pr Daniel Worthley
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依托单位:
Gastrointestinal mesenchyme supports intestinal stem cells, promotes intestinal regeneration and drives cancer.
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批准号:nhmrc : GNT1081852
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项目类别:Project Grants
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资助金额:$53.19万
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财政年份:2015
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负责人:A/Pr Daniel Worthley
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依托单位:
The origin, contribution and molecular characteristics of myofibroblasts in gastric carcinogenesis
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批准号:nhmrc : 607426
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项目类别:Early Career Fellowships
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资助金额:$32.36万
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财政年份:2010
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负责人:A/Pr Daniel Worthley
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依托单位:
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