MODES OF DEATH, FREQUENCY OF HEALED AND ACUTE MYOCARDIAL INFARCTS

死亡模式、愈合或急性心肌梗死（MI）的频率 或两者兼有，严重狭窄的主要心外膜冠状动脉数量 889例尸检时研究了动脉粥样硬化斑块和心脏重量 年龄≥ 30岁的致死性动脉粥样硬化性冠状动脉疾病患者 动脉疾病（CAD）。没有患者接受过冠状动脉搭桥手术或 冠状动脉成形术 889名患者被分为4个主要组，每个主要组 分为2个亚组：1）急性心肌梗死无（306例）和（119例） 患者）心肌梗死治愈; 2）院外突然死亡，无（121 患者）和（118例患者）MI已治愈; 3）慢性充血性心脏病 心力衰竭（CHF）伴MI愈合，无（137例患者）和有（33例患者） 患者）左心室动脉瘤;和4）院内猝死 无不稳定型心绞痛20例，有不稳定型心绞痛35例。的 687名男性（77%）的平均年龄为60 ± 11岁。在202名女性中， (23%），68 ± 13岁（p=.0001）。在研究的患者中，53%的患者有全身性 高血压、心绞痛39%、糖尿病33%。880人中 415例（48%）患者有1个或多个肉眼可见的左心室瘢痕。 889例患者中超过一半（51%）有3或4例（包括左主干）严重 心外膜冠状动脉横截面积缩小>75%， 动脉粥样硬化斑块男性的平均心脏重量为505 ± 110 g， 202例女性427 ± 94克（男性<400克，女性<350克） （P= 0.0001），只有20%的患者心脏重量正常。

Modes of death, frequency of a healed or an acute myocardial infarct (MI) or both, numbers of major epicardial coronary arteries severely narrowed by atherosclerotic plaque, and heart weight were studied at necropsy in 889 patients aged 30 years of age or older with fatal atherosclerotic coronary artery disease (CAD). No patient had had a coronary bypass operation or coronary angioplasty. The 889 patients were divided into 4 major groups and each major group was divided into 2 subgroups: 1) acute MI without (306 patients) and with (119 patients) a healed MI; 2) sudden out-of-hospital death without (121 patients) and with (118 patients) a healed MI; 3) chronic congestive heart failure (CHF) with a healed MI without (137 patients) and with (33 patients) a left ventricular aneurysm; and 4) sudden in-hospital death without (20 patients) or with (35 patients) unstable angina pectoris. The mean age of the 687 men (77%) was 60 + 11 years. and of the 202 women (23%), 68 + 13 years (p=.0001). Of the patients studied, 53% had systemic hypertension, 39% angina pectoris, and 33% diabetes mellitus. Of the 880 patients, 415 (48%) had 1 or more grossly visible left ventricular scars. Over half (51%) of the 889 patients had 3 or 4 (includes left main) major epicardial coronary arteries narrowed >75% in cross-sectional area by atherosclerotic plaque. The mean heart weight in the men was 505 + 110 g, and in the 202 women, 427 + 94 & (normal in men <400 g; in women, <350 g) (P=.0001), and only 20% of the patients had a heart of normal weight.