ATHEROSCLEROTIC PLAQUES IN SUDDEN DEATH AND IN MYOCARDIAL INFARCTION

我们研究了4个主要的尸检动脉粥样硬化斑块成分。 (右、左主干、左前降和左回旋) 心外膜冠状动脉病变死亡15例临床分析 急性心肌梗死(AMI)和12例突发心肌梗死 冠状动脉死亡(SCD)合并急性心肌梗死。在急性心肌梗塞组内和在SCD内 组内，在斑块成分方面没有任何差异 四条主要的心外膜冠状动脉。在两组中，斑块 形态作为横截面面积变窄的函数而变化 细分市场。在两组中，致密的相对脱细胞的数量 纤维组织、钙化组织和牙髓碎屑在 横截面面积收窄程度增加的线性方式 以及细胞纤维组织的数量减少 线性的。在急性心肌梗死组，斑块的百分比包括 牙髓碎屑和细胞纤维组织明显分离 较窄(&lt；75%)的管段变窄(&gt；75%的横截面面积) 细分市场。急性心肌梗死组与慢性阻塞性肺病组的比较显示 有显著差异。

We studied at necropsy atherosclerotic plaque composition in the 4 major (right, left main, left anterior descending, and left circumflex) epicardial coronary arteries in 15 patients who died of consequences of an acute myocardial infarction (AMI) and in 12 patients with sudden coronary death (SCD) with AMI. Within the AMI group and within the SCD group, there were no differences in plaque composition among any of the four major epicardial coronary arteries. Within both groups, plaque morphology varied as a function of cross-sectional-area narrowing of the segments. In both groups, the amount of dense relatively acellular fibrous tissue, calcified tissue, and pultaceous debris increased in a linear fashion with increasing degrees of cross-sectional-area narrowing of the segments, and the amount of cellular fibrous tissue decreased linearly. In the AMI group, the percentage of plaque consisting of pultaceous debris and of cellular fibrous tissue separated significantly narrowed (>75% cross-sectional area) segments from less narrowed (<75%) segments. A comparison of the AMI group to the SCD group showed significant differences.