USEFULNESS OF TOTAL 12-LEAD QRS VOLTAGE COMPARED TO OTHER CRITERIA

12 导联 QRS 总电压与其他标准相比的有用性

• 批准号: 3899224
• 负责人: W C ROBERTS
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3899224
• 关键词: diagnosis quality /standard; electrocardiography; heart dimension /size; heart disorder diagnosis; human subject; intracardiac pressure; intracardiac volume; ventricular hypertrophy

The sensitivity of the total 12-lead QRS amplitude was compared to certain standard electrocardiographic criteria for left ventricular (LV) hypertrophy in 57 necropsy patients with hypertrophic cardiomyopathy (HC). The total 12-lead QRS amplitude ranged from 66 to 339 mm (mean 179) (10 mm = 1 mV). Using 175 mm as the upper limit of normal, this technique yielded a sensitivity of 53% which was the highest sensitivity of any criteria tested. The Sokolow-Lyon index had a sensitivity of 39%; the Romhilt-Estes voltage criteria, 37%; the Romhilt-Estes point score system, 49%, and the criterion of RV6 > RV5, 39%. No correlation was found between total 12-lead QRS voltage and heart weight, LV free wall thickness, LV peak systolic and end-diastolic pressures or LV outflow tract peak systolic pressure gradient. The 10 patients (18%) with transmural LV scars had significantly lower total 12-lead QRS voltage than did the 48 patients (78%) without such scars (155 mm - vs. - 205 mm, p=0.02). Total 12-lead QRS amplitude >175 mm is a useful indicator of LV hypertrophy, and among patients with HC it is more sensitive than other more commonly employed criteria.

总的12导联QRS振幅的灵敏度与某些 左心室（LV）的标准心电图标准 57例肥厚型心肌病（HC）尸检患者的心肌肥厚。 12导联QRS总振幅范围为66 ~ 339 mm（平均179 mm）（10 mm = 1 mV）。使用175 mm作为正常上限，该技术产生了 敏感性为53%，是所有标准中最高的敏感性 测试. Sokolow-Lyon指数的敏感性为39%，Romhilt-Estes指数的敏感性为39%。 电压标准，37%; Romhilt-Estes评分系统，49%， RV 6> RV 5的标准为39%。未发现12导联心电图与 QRS电压和心脏重量、LV游离壁厚度、LV收缩期峰值和 舒张末期压或LV流出道峰值收缩压 梯度离心10例（18%）有透壁性LV瘢痕的患者， 总12导联QRS电压低于48例患者（78%）， 瘢痕（155 mm vs. - 205 mm，p=0.02）。12导联QRS总振幅>175 mm 是左心室肥大的有用指标，在HC患者中， 比其他更常用的标准更敏感。