眼神经胶质细胞参与葡萄膜炎的研究-猫眼课题宝

眼神经胶质细胞参与葡萄膜炎的研究

批准号：

3941670

负责人：

F ROBERGE

金额：

$0.0万

依托单位：

NATIONAL EYE INSTITUTE

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/3941670

关键词：

T lymphocyte cell cell interaction cellular pathology glia helper T lymphocyte immunopathology immunopharmacology inflammation retina surface antigens tissue /cell culture uvea uveitis

项目摘要

项目成果

F ROBERGE的其他基金

相似基金

相关文献

中文摘要

翻译

这项工作扩展了我们正在进行的研究

英文摘要

The work extended our ongoing study of interactions between the retinal glial Muller cell and T lymphocytes. In an in vitro co- culture system, Muller cells had been shown to exert a profound inhibitory influence on antigen and IL-2 driven proliferation of T helper cell lines. Investigations of the nature of the inhibitory moiety revealed that it was sensitive to proteinase. In further studies, we demonstrated that Muller cells can produce interleukin 1 (IL-1) activity and that in conditions where their inhibitory action is removed they display the capacity to efficiently function as antigen presenting cells.

期刊论文(0)

专著(0)

科研奖励(0)

会议论文