MR GUIDED THERMAL ABLATION OF ABDOMINAL TUMORS
MR GUIDED THERMAL ABLATION OF ABDOMINAL TUMORS
批准号:
6115296
负责人:
JONATHAN S LEWIN
金额:
$1.92万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30
中文摘要
本试验的目的是:描述磁共振(MR)引导下软组织转移瘤热消融的安全性,并描述使用射频(RF)发生器作为热源通过热消融在肿瘤内产生的肿瘤坏死分数。 患者仅为标准措施干预失败的实体瘤患者或认为全身治疗无效的患者。 患者不得接受手术切除。有8例患者接受了治疗(11例入组)。 3例患者入组接受不同病变的消融。 迄今为止,1例受试者达到完全缓解,5例入组患者病情稳定,3例发生疾病进展,1例患者被取消,最后1例患者未进行分析。 这项试验继续增加病人。
英文摘要
The objectives of this trial are: to describe the safety of Magnetic Resonance (MR) guided thermal ablation of soft tissue metastases and to describe the fraction of tumor necrosis that can be generated within tumors through thermal ablation using a radiofrequency (RF) generator as the heat source. Patients are only those with solid tumors that have failed intervention with standard measures or those for which systemic therapy was considered ineffective. Patients must not be candidates for surgical resection. There have been eight patients treated (11 enrollments). Three patients were enrolled for ablation of different lesions. To date one subject achieved a complete response, five enrollments had stable disease, three developed progressive disease, one patient was cancelled and the last has not been analyzed. This trial continues to accrue patients.
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