COLLABORATIVE HOME INFANT MONITORING EVALUATION (CHIME)

本方案是一项家庭婴儿呼吸暂停治疗的多中心协作试验。 这些设备用于监测被认为有SIDS风险的婴儿以及正常对照组的呼吸和心率。 本研究将产生关于呼吸暂停监测仪的有效性、准确性以及这些器械检测临床重要事件的能力的广泛描述性信息。 除了家庭监护仪外，婴儿还接受了夜间多导睡眠图和标准化发育测试。 对婴儿的随访持续到大约1.5岁。GCRC心理测量师协助进行发育评估。 每年约有400-500名患者接受筛查，平均入组37人。 迄今为止，共入组了195例受试者。 CHIME研究的招募于1998年2月28日结束，大学医院的33名婴儿和MetroHealth的14名婴儿处于1年随访期。

This protocol is a multicenter collaborative trial of Home Infant Apnea Monitors. These devices are used to monitor breathing and heart rate in infants thought to be at risk for SIDS, as well as, normal controls. This study will yield extensive descriptive information regarding the efficacy of apnea monitors, their accuracy, and the ability of these devices to detect clinically important events. In addition to the home monitor, the babies are evaluated with overnight polysomnography and standardized developomental testing. The follow-up of the infants continues until approximately age 1.5 yrs. The GCRC Psychometrist assists with the developmental assessments. Approximately 400-500 patients are screened each year with an average enrollment of 37. A total of 195 subjects have been enrolled to date. Recruitment for the CHIME study ended 2/28/98 and 33 infants at University Hospitals and 14 from MetroHealth are in the 1 year follow-up period.