Training in Neonatal Research

描述(由申请者提供)：新培训的医生/科学家迫切需要进入新生儿学的学术生涯。几十年来，彩虹婴儿和儿童医院的新生儿科一直在培训团契毕业生，让他们在新生儿学领域担任国内和国际的领导角色。我们为我们在T32最初的资助周期中取得的成就感到自豪，其中包括将所有五名T32研究员安置在学术教师职业生涯中，以及TGE申请者池的显著增加。在这份提案中，我们将通过重点介绍我们在呼吸神经生物学、脑发育、神经发育结局和炎症方面的现有科学优势，使受训人员能够应对广泛的新生儿疾病。我们拥有一支成就卓著的医学博士和博士导师队伍，在这三个主题领域拥有科学专长，包括基础翻译研究和以患者为导向的研究。我们将招募实习生进行为期两年的密集培训 在这些专题领域之一的现有研究人员的指导下沉浸研究。导师指导委员会可以包括“近乎同行”的初级教员，作为受训教师的榜样，以及高级教员导师。由于学员的主要导师经验是成功的关键，我们选择了在医生/科学家培训方面拥有良好记录的导师，并将密切监控学员/导师关系。受训者将接受结构良好的教学计划，为学术生涯发展提供所有必要的技能。选修课程活动 将为选定的基础科学或流行病学研究领域[例如，授予临床研究理学硕士学位]而设计。监督将通过严格的内部指导委员会审查和外部审查委员会进行，该委员会由在新生儿学领域备受尊敬的学术领袖组成。已经启动了新的战略，以招募少数群体和其他处境不利的候选人，以确保多样化的受训人员致力于成功地从研究金过渡到以改善新生儿健康为重点的基本转化性研究或以病人为中心的研究。总而言之，我们准备在之前T32筹资周期的成功基础上，将新的有经验的调查人员纳入现有的导师库中，所有这些导师都专注于神经呼吸成熟和炎症途径，这些途径导致了最终的发病率。

DESCRIPTION (provided by applicant): There is a profound need for newly trained physician/scientists to enter academic careers in Neonatology. The Division of Neonatology at Rainbow Babies & Children's Hospital has, for several decades, trained fellowship graduates to assume national and international leadership roles in Neonatology. We are proud of our accomplishments in the initial funding cycle of this T32 which include placement of all five T32 fellows in academic faculty careers, and a marked increase in the pool of TGE applicants. In this proposal we will enable trainees to address a broad spectrum of neonatal morbidities by focusing on our existing scientific strengths in respiratory neurobiology, brain development, and neurodevelopmental outcome and inflammation. We have an accomplished M.D. and Ph.D. mentoring faculty with scientific expertise in these three thematic areas, encompassing both basic translational and patient oriented research. We will recruit trainees to a two-year intensive research immersion under the mentorship of established investigators within one of these thematic areas. A mentorship committee may include "near peer" junior faculty preceptors to serve as trainee role models in addition to senior faculty mentors. As the primary mentor experience of the trainee is critical for success, we have chosen mentoring faculty with a strong track record for physician/scientist training, and will provide close monitoring of the trainee/mentorship relationship. Trainees will be exposed to a well-structured didactic program to provide all the necessary skills for academic career development. Optional curricular activities will be designed for the chosen field of basic science or epidemiologic research [e.g., award of a Master's of Science degree in Clinical Research]. Oversight will occur via both stringent Internal Steering Committee review and an External Review Committee of highly regarded academic leaders in Neonatology. New strategies have been initiated to recruit minority and otherwise disadvantaged candidates to ensure a diversity of trainees committed to a successful transition from fellowship to basic translational or patient-oriented research focused on improving neonatal health. In summary, we are poised to build upon the success of our prior T32 funding cycle by incorporating new experienced investigators into the existing pool of mentors, all of whom are focused on neurorespiratory maturation and inflammatory pathways that contribute to resultant morbidities.