CONFERENCE--FASEB SMOOTH MUSCLE

要求为将于2000年7月22日至27日在科罗拉多斯诺马斯举行的2000年FASEB平滑肌会议提供部分资金。这是自1982年以来每3年举行一次的非常成功的平滑肌会议系列中的第7次。FASEB平滑肌会议被认为是平滑肌生物学研究人员的首要论坛，来自澳大利亚，亚洲，欧洲和北美的研究人员参加了会议。 了解平滑肌功能对于那些对心血管、呼吸、生殖、消化和泌尿道生理学和病理生理学感兴趣的人至关重要。该会议定期吸引来自多个学科的基础科学和临床研究人员。 近年来，分子生物学、细胞和亚细胞共聚焦成像、膜片钳等技术的应用取得了快速进展，在肌丝相互作用、平滑肌发育和可塑性、离子通道特性和调控、第二信使系统、Ca2+信号传导和细胞间相互作用等方面获得了新的认识。由于许多平滑肌研究人员在特定的器官系统上工作，并经常参加与这些器官系统的具体情况有关的社会会议，因此讨论有关平滑肌生物学的常见问题的全面平滑肌会议是非常重要的。FASEB平滑肌会议已经为这一关键需求服务了20年。会议的形式特别有利于进行非正式讨论，并有机会提出新的想法。除了在申请中描述的计划讲座，并组织成9个专题研讨会，从年轻的研究人员的贡献将从提交的摘要中选择，并添加到专题研讨会作为口头陈述。2000年FASEB平滑肌会议将全面回顾平滑肌生物学的最新进展，并为开始在该领域进行研究的科学家或对平滑肌功能具有更广泛临床兴趣的临床研究者提供一个密集的短期课程。非正式互动的广泛机会将使各级调查人员能够结识新同事，探索新的想法和技术，并开展新的合作。

Partial funding of the 2000 FASEB Smooth Muscle Conference to be held from July 22-27th, 2000 at Snowmass, Colorado is requested. This is the 7th in a highly successful series of smooth muscle meetings held every 3 years since 1982. The FASEB Smooth Muscle Conferences are regarded as the premier forum for researchers in smooth muscle biology, and the meetings are attended by investigators from Australia, Asia, Europe and North America. Understanding smooth muscle function is vital to those interested in cardiovascular, respiratory, reproductive, digestive and urinary tract physiology and pathophysiology. This conference regularly attracts both basic science and Clinical investigators from several disciplines. Rapid progress has been made during the past 3 years using techniques such as molecular biology, cellular and sub-cellular confocal imaging, and patch clamping, and new insights have been gained about myofilament interactions, development and plasticity of smooth muscles, ion channel identity and regulation, second messenger systems, Ca2+ signaling, and cell-to-cell interactions. Because many smooth muscle investigators work on specific organ systems and frequently attend society meetings related to the specifics of these organ systems, a comprehensive smooth muscle meeting where common issues regarding smooth muscle biology are discussed is extremely important. The FASEB Smooth Muscle Conferences have served this critical need for 2 decades. The format of the meeting is especially conducive to informal discussion and opportunities to develop new ideas. In addition to the programmed lectures described in the application and organized into 9 topical symposia, contributions from young investigators will be selected from abstracts submitted and added to the symposia as oral presentations. The 2000 FASEB Smooth Muscle Conference will provide a comprehensive review of recent progress in smooth muscle biology and constitute an intensive short course for scientists who are beginning investigations in the field or clinical investigators with broader clinical interests in smooth muscle function. The extensive opportunities for informal interactions will allow investigators at all levels to meet new colleagues, explore new ideas and techniques, and develop new collaborations.