A new monocyte atherogenic phenotype in chronic HIV disease.

澳大利亚大多数艾滋病毒阳性者现在死于心血管疾病，由动脉粥样硬化或冠状动脉增厚引起。一种称为单核细胞的白色血细胞预防动脉粥样硬化的能力在HIV中受损。该项目旨在了解艾滋病毒是如何做到这一点的，以及我们如何扭转这种影响。了解这些过程也将有助于改善治疗方法，以减少患有其他慢性炎症疾病的人的心脏病。

Most HIV+ people in Australia now die from cardiovascular disease, caused by atherosclerosis or thickening of coronary arteries. The ability of a white blood cell called the monocyte to prevent atherosclerosis is impaired in HIV. This project aims to understand how HIV does this and how we can reverse the effect. Understanding these processes will also help improve treatments to reduce heart disease in people with other chronic inflammatory conditions.