CORE--CLINICAL

作为一个统一的项目来完成子项目的主要优点之一是， 计划项目是临床核心提供的核心支持。的 临床核心的目的是招募和评估适当的 在子项目中的实验组。其中包括随机 将受试者分配至治疗组。此外，评估 所有预计人员共享的数据分析活动将由 临床核心因此，临床核心将提供术前和术后 干预数据收集和语言样本收集与分析 所有子项目。因为这些服务将是外部的， 个别子项目，由核心工作人员完成， 子项目的目的，整个实验的严格性， 计划项目将得到加强。该核心由PI指导， 比尔·威尔克森中心（Bill Wilkerson Center），听力和言语部（Division of Hearing and Speech） 范德比尔特大学医学院的科学。因为该法案 威尔克森中心是一个主要的转介网站的讲话，语言， 听证服务的地理范围很广，有很大的 为子项目招募受试者的覆盖基地。更 对于项目的目的来说，重要的是， 中心服务的语言障碍儿童人口， 将被用于项目。完成的程序 本节介绍了临床核心活动。

One of the primary advantages in completing the subprojects as a unified program project is the central support provided by the clinical core. The purpose of the clinical core is to recruit and assess appropriate experimental groups within the subprojects. This includes the random assignment of subjects to treatment groups. In addition, the assessment and data analysis activities shared by all projected will be provided by the clinical core. Thus, the clinical core will provide the pre- and post- intervention data collection and language sample collection and analysis to all subprojects. Because these services will be external to the individual sub-project and completed by core staff who will be bland to the purposes of the subprojects, the overall experimental rigor of the program project will be enhanced. This core is directed by the PI and housed in the Bill Wilkerson Center in the Division of Hearing and Speech Sciences at Vanderbilt University School of Medicine. Because the Bill Wilkerson Center is a primary referral site for speech, language, and hearing services for a substantial geographical area, there is a large catchment base for recruiting subjects to the subprojects. More importantly for the purposes of the program project, there is an ample population of children with language impairments served by the Center that will be available to the program project. The procedures for completing the clinical core activities are presented in this section.