CORE--CLINICAL

完成统一的子项目的主要优势之一是 计划项目是临床核心提供的中心支持。这个 临床核心的目的是招募和评估适当的 子项目内的试验组。这包括随机 将受试者分配到治疗组。此外，评估还包括 所有计划共享的数据分析活动将由 临床核心。因此，临床核心将提供前后的 干预数据收集和语言样本收集与分析 所有的子项目。因为这些服务将在 单个子项目，并由核心员工完成，他们将平淡无奇地 子项目的目的，总体上实验的严格性 计划项目将得到加强。这个核心是由PI和 住在比尔·威尔克森中心的听力和语音科 范德比尔特大学医学院的理科专业。因为本条例草案 威尔克森中心是一个主要的推荐站点，提供语音、语言和 听证服务的地域相当大，有很大的 为子项目招募受试者的集水区。更多 重要的是，为了计划项目的目的，有足够的 该中心为语言障碍儿童提供服务的人口 将可用于计划项目。填写的程序 本节介绍了临床核心活动。

One of the primary advantages in completing the subprojects as a unified program project is the central support provided by the clinical core. The purpose of the clinical core is to recruit and assess appropriate experimental groups within the subprojects. This includes the random assignment of subjects to treatment groups. In addition, the assessment and data analysis activities shared by all projected will be provided by the clinical core. Thus, the clinical core will provide the pre- and post- intervention data collection and language sample collection and analysis to all subprojects. Because these services will be external to the individual sub-project and completed by core staff who will be bland to the purposes of the subprojects, the overall experimental rigor of the program project will be enhanced. This core is directed by the PI and housed in the Bill Wilkerson Center in the Division of Hearing and Speech Sciences at Vanderbilt University School of Medicine. Because the Bill Wilkerson Center is a primary referral site for speech, language, and hearing services for a substantial geographical area, there is a large catchment base for recruiting subjects to the subprojects. More importantly for the purposes of the program project, there is an ample population of children with language impairments served by the Center that will be available to the program project. The procedures for completing the clinical core activities are presented in this section.