CORE--BIOSTATISTICS AND DATA MANAGEMENT FACILITY

生物统计学和数据管理核心的主要作用是在作为本提案一部分开展的临床和实验室研究的设计、实施和分析的定量方面提供协作。在实验室和临床研究中，这将包括样本量计算和摘要、手稿和演示文稿的数据分析。对于临床研究，还将包括样本量计算和摘要、手稿和演示文稿的数据分析。对于临床研究，还将包括方案审查、表格开发、数据提取、数据计算机化和质量控制。核心的具体目标包括：1。为临床方案设计以及相关方案的计划和解释序列提供生物统计学专业知识。2.为实验室研究的设计、分析和解释提供生物统计学帮助。3.为临床方案提供表格设计、数据管理支持和质量控制。4.为收集个体患者信息提供临床数据管理。5.为正在进行的研究提供中期报告，并对最终研究结果进行更详细的统计分析;通过摘要，手稿和演示文稿合作传播这些结果。6.使用BMT数据库进行统计分析，以比较结局，并在适当时确定方案间的预后因素。

The primary role of the Biostatistics and Data Management Core is to provide collaboration on quantitative aspects of the design, conduct, and analysis of the clinical and laboratory studies undertaken as part of this proposal. In both the laboratory and the clinical studies this will include sample size calculation and analysis of data for abstracts manuscripts and presentations. For the clinical studies, will also include sample size calculation and analysis of data for abstracts, manuscripts and presentations. For the clinical studies, will till also include protocol review, forms development, dat extraction, data computerization and quality control. Specific aims of the core include: 1. To provide biostatistical expertise for clinical protocol design and for planning and interpreting sequences of related protocols. 2. To provide biostatistical assistance in the design, analysis, and interpretation of laboratory studies. 3. To provide forms design, data management support, and quality control for clinical protocols. 4. To provide clinical data management for collection of individual patient information. 5. To provide interim reports for ongoing studies, and more detailed statistical analyses of finally study results; to collaborate on dissemination of these results through abstracts, manuscripts, and presentations. 6. To conduct statistical analyses using the BMT data base to compare outcomes and identify prognostic factors across protocols when appropriate.