Mapping the integration of T cell fate control across time and space

该项目旨在应用新方法来确定信号复合物的协调如何影响适应性免疫系统细胞的命运。它希望确定信号环境如何协调细胞的命运，如分化、死亡和增殖。该项目预计将为进一步研究广泛的生物学问题提供一个实验和分析平台，并为这一基本问题提供新的知识。该平台应支持进一步的工作，最终为组织和免疫细胞再生提供新的模型，并为人类和牲畜治疗提供新的制造平台，以及其他好处。

This project aims to apply new methods to determine how coordination of signalling complexes impacts upon the fate of cells of the adaptive immune system. It expects to determine how the context of signallng orchestrates cell fates such as differentiation, death and proliferation. The project is expected to yield an experimental and analytical platform for further investigations into a broad range of biological questions, and to provide new knowledge of this fundamental problem. This platform should support further work that ultimately provides new models for tissue and immune cell regeneration, and new manufacturing platforms for therapies for humans and livestock, among other benefits.