MENTORING NEUROSCIENCE IN LOUISIANA

描述（由申请人提供）：LSU-HSC领导四个伙伴关系 路易斯安那州的一个机构在进行COBRE神经科学研究。程序 主任和既定的科学家是导师，选择，非常有前途的 初级教师谁提出了四个研究项目，已被设计为 指导的共同目标，以建立新的国家竞争力的研究。 科学的重点是神经生物学的一个中心问题：了解 突触可塑性和神经元存活的细胞和分子基础 对阐明神经系统疾病的病理生理学至关重要，例如： 中风、神经创伤和神经变性疾病。这种多学科 计划涉及细胞神经生理学，分子生物学和行为 神经科学为支持COBRE项目，核心资源包括 脂质信使和分子的成像、神经化学设施 神经生物学第二至第五年的招聘计划进一步有利于 通过积极吸引新的研究人员， 将在资深神经科学家的指导下工作。一 所需行政核心资金相对较少。具体目标 实现这些目标是：1）促进教师发展， 研究项目; 2）进一步发展具有竞争力的关键质量 通过招募、启动、指导和 保留新的教员; 3）加强基础设施的关键 通过开发三个核心技术来扩大路易斯安那州的神经科学能力 在LSUHSC的研究模块; 4）提供科学和granimate 指导和加强促进互动的支持网络; 5)实施中期和成果评估，以保持这一COBRE 计划在轨道上。这种合作关系依赖于我们公司现有的专业知识和 决定建立一个科学上成功的神经科学联盟， 方面应受中华四名目标教师和四名拟招聘教师是 实现这些目标的关键基石。核心资源是 这对这个联盟的整体成功至关重要，不仅在神经科学领域， 在所有生物医学科学中。指导初级教师的计划， 征聘计划将确保源源不断的新的具有国家竞争力的人员， 路易斯安那州的神经科学家

DESCRIPTION (provided by applicant): The LSU-HSC leads a partnership of four Louisiana institutions in a COBRE on neuroscience research. The Program Director and established scientists are mentors to selected, highly promising junior faculty who propose four research projects that have been designed for the common goal of mentoring to build new nationally competitive research. The scientific focus is on a central issue of neurobiology: to understand the cellular and molecular basis of synaptic plasticity and neuronal survival critical to clarify the pathophysiology of neurological disorders such as: stroke, neural trauma and neurodegenerative diseases. This multidisciplinary program involves cellular neurophysiology, molecular biology and behavioral neuroscience. To support the COBRE projects, core resources include facilities for imaging , neurochemistry of lipid messengers and molecular neurobiology. A recruitment plan for years 2 to 5 further benefits the collaborating institutions by actively attracting new research faculty who will work under the guidance of established neuroscientists as mentors. A relatively small administrative core funding is requested. The specific aims to attain these objectives are: 1) to promote faculty development through research projects; 2) to further develop a critical mass of competitive extramurally funded investigators by the recruitment, start up, mentoring and retention of new faculty members; 3) to enhance the infrastructure critical for expanding neuroscience capability in Louisiana by developing three core research modules at LSUHSC; 4) to provide scientific and grantsmanship mentoring and strengthen the support network that promotes interactions; and 5) to implement interim and outcome evaluations so as to keep this COBRE program on track. This partnership rests on existing expertise and in our firm decision to build a scientifically successful neuroscience alliance in Louisiana. The four target faculty and the four to-be-recruited faculty are the critical building blocks to achieve these goals. The core resources are vital to the overall success of this consortium, not only in neuroscience but in all the biomedical sciences. The plans for mentoring junior faculty and the recruitment plan will ensure a steady stream of new nationally competitive neuroscientists in Louisiana.