Institute on Aging Clinical Translational Research Building

描述（由申请人提供）：佛罗里达州拥有全国60岁或以上人口的最大比例（17.8%），这一年龄组代表了人口增长最快的部分。在2000年美国人口普查中，超过320万佛罗里达人，或该州人口的22.2%，报告有残疾。随着人口的不断老龄化和老年美国人全职或季节性地搬迁到我们州，佛罗里达的残疾美国人数量将增加。老年人有许多独特而复杂的医疗保健需求，因此，佛罗里达州的学术医疗中心面临着开发研究项目和研究设施的重大挑战，可以解决老年人的特殊健康问题。为了应对日益增长的医疗保健需求和老龄化社区人口的增加，我们建议建造39，500 GSF的佛罗里达大学（UF）老龄化临床转化研究所大楼（IOA-CTRB），这将有助于开发新的研究方法，旨在改善美国老年人的健康，独立性和生活质量。 虽然需要一个全面的设施是大量的，一个可比的资源，以拟议的IOA- CTRB是完全缺乏在UF校园和佛罗里达。IOA-CTRB将创造一个有凝聚力的环境，促进对老龄化和残疾问题研究的整体方法。为了有效地满足老年人群的临床研究需求，并促进转化研究的各个阶段，我们建议建造39，500 GSF的IOA-CTRB，这是一座能源和环境设计（LEED）白金建筑，将容纳以下新的共享资源：临床研究评估设施，生物标本处理和储存，招募和保留核心，行为和生活方式改变干预设施，流行病学实验室和老龄化健康服务，创造性思维的办公中心，会议和培训资源，以及无障碍停车场。 IOA-CTRB将在刺激和维持UF和该地区的老龄化研究和研究职业发展方面发挥重大的校园影响。该IOA-CTRB申请的主要优势是强大的项目领导力，保留或创造的大量美国就业机会，卓越的机构支持，IOA-CTRB提供的独特的单点进入资源，创新的先进绿色/可持续设计和生活质量原则，特殊的资助和待IOA赠款记录，影响深远的研究职业发展计划，新的认知老化和记忆临床转化研究计划（CAM-CTRP），最重要的是NIH和CDC资助的中心赠款，如胡椒老年美国人独立中心（OAIC），临床转化科学研究所（CTSI）和佛罗里达残疾健康办公室（FOHD）在佛罗里达是独一无二的。这些中心赠款代表了IOA的研究和研究职业发展骨干，并支持老龄化领域和IOA-CTRB的当前和未来资助赠款的实施和长期可持续性和成功。总的来说，所有这些资产最终将对美国老年人的健康、独立性和生活质量产生积极影响。 该提案将为建设项目创造或保留总共283个工作岗位，并将在新设施中创造或保留93个工作岗位。总体影响将是创造或保留376个美国就业岗位。

DESCRIPTION (provided by applicant): The state of Florida has the largest proportion (17.8%) of persons age 60 years or older in the nation and this age group represents the fastest growing segment of the population. In the 2000 US Census, more than 3.2 million Floridians, or 22.2% of the state's population, reported having a disability. As the population continues to age and older Americans relocate full-time or seasonally to our state, the number of disabled Americans in Florida will rise. Older adults have a number of unique and complex health care needs, and as such, academic medical centers in the state of Florida face a significant challenge to develop research programs, and research facilities that can address the special health problems of older persons. In response to the growing health care needs and increasing population of the aging community, we propose to construct the University of Florida (UF) Institute on Aging Clinical Translational Research Building (IOA-CTRB) of 39,500 GSF, which will be instrumental for developing novel research approaches aimed at improving the health, independence and quality of life of older Americans. While the need for a comprehensive facility is substantial, a comparable resource to the proposed IOA- CTRB is completely lacking on the UF campus and in Florida. The IOA-CTRB will create a cohesive environment that will promote a holistic approach to research on aging and disability. To effectively address the emerging clinical research needs regarding the older populations and to promote all stages of translational research we propose to construct the IOA-CTRB of 39,500 GSF, a Leadership in Energy and Environmental Desing (LEED) platinum building, which will host the following new shared resources: clinical research assessment facility, biological specimens processing and repository, recruitment and retention core, behavioral and lifestyle modification intervention facility, laboratory of epidemiology and health services of aging, office hub for creative thinking, conference and training resources, and accessible parking. The IOA-CTRB will exert a major campus-wide impact in stimulating and sustaining research and research career development on aging at UF and in the region. Major strengths of this IOA-CTRB application are strong project leadership, sizeable number of American jobs retained or created, remarkable institutional support, unique single point of entry resources offered by the IOA-CTRB, innovative advanced green/sustainable design and quality of life principles, exceptional funded and pending IOA grant record, far reaching research career development programs, new Cognitive Aging and Memory Clinical Translational Research Program (CAM-CTRP), and most importantly NIH and CDC funded center grants, such as the Pepper Older Americans Independence Center (OAIC), the Clinical Translational Sciences Institute (CTSI) and the Florida Office on Disability Health (FOHD) that are unique in Florida. These center grants represent the research and research career development backbone for the IOA and support the implementation and long- term sustainability and success of the current and future funded grants in the area of aging and of the IOA- CTRB. Taken together, all these assets will ultimately positively impact on the health, independence and quality of life of older Americans. This proposal will create or retain a total of 283 jobs for the construction project and 93 jobs will be created or retained in the new facility. The total impact will be on the creation or retention of 376 American jobs.