ERP & Behavioral Predictors of Language Intervention

描述(申请人提供)：拟进行两项研究。第一项研究将试图澄清患有特定语言障碍(SLI)的学龄前儿童语音处理缺陷的程度。第二项研究试图确定两种语言干预在SLI儿童中的相对优势是否取决于治疗前的言语处理能力及其行为相关性。这个项目将招募60名患有系统性红斑狼疮的儿童，这些儿童处于布朗的I-IV阶段。此外，60名年龄、性别、种族和社会地位相匹配的典型发育儿童将被用来回答研究1的问题。在进入研究时，将测试语言和言语处理能力。语音处理将用事件相关电位和行为测量来衡量。在第二项研究中，SLI儿童将被随机分配到两个治疗组中的一个：环境语言教学(MLT)或广泛目标重铸(BRT)治疗。这些儿童将以1：1的形式接受治疗，每次30分钟，每周3次，为期6个月。语法测试将在治疗阶段进行两次，在治疗结束后立即进行，并在两个后续阶段进行。表现力和接受性的语言和语音处理的一般措施将在最后一节课中重复。将使用多元回归、多元排列检验和增长曲线分析来检验研究问题。要求提供五年的资金。

DESCRIPTION (provided by applicant): Two studies are proposed. The first study will seek to clarify the extent to which preschoolers with specific language impairment (SLI) have speech processing deficits. The second study seeks to determine whether the relative superiority of two language interventions in children with SLI depends on pretreatment speech processing ability and its behavioral correlates. Sixty children with SLI in Brown's stage I - IV will be recruited in this project. Additionally, 60 typically developing children matched for age, gender, ethnicity, and SES will be used to address the questions for Study 1. At entry into the study, language and speech processing will be tested. Speech processing will be measured with event-related potential and behavioral measures. For study two, the SLI children will be randomly assigned to one of two treatment groups: Milieu Language Teaching (MLT) or Broad-Target Recast (BRT) treatment. These children will receive treatment in a 1:1 format for 30 minutes/session, 3/week for 6 months. Grammar will be tested again twice during the treatment phase, immediately after treatment, and at two follow-up periods. General measures of expressive and receptive language and speech processing will be repeated at the last period. Multiple regression, multivariate permutation tests, and growth curve analyses will be used to test the research questions. Five years of funding are requested.