Child Health Research Career Development Award

描述(由申请者提供)：哥伦布儿童医院儿童健康研究职业发展奖(CCH-CHRCDA)的长期目标是培养新的儿科医生-科学家。由于过去十年生物医学科学的快速发展，迫切需要加快将基础科学发现转化为临床应用，这将有利于儿童的健康。作为一个大型、多学科的儿科(俄亥俄州立大学)，在一家专门为儿童护理(CCH)的医院，我们处于推动这一事业的理想地位。我们将继续我们现有CHRCDA的主题，用于这一相互竞争的更新应用-儿科分子医学。虽然自1996年我们最初应用以来，科学和医学取得了快速发展，但我们选择主题的基本前提只是得到了验证。我们为过去四年取得的成就感到自豪。我们的前三位CHRCDA学者都先后获得了NIH R01的独立资助。包括我们目前正在接受CHRCDA资助的3名学者，50%(3/6)是妇女，17%(1/6)是少数民族(非洲)。对研究和CHRCDA的机构支持从未像现在这样强大。在过去的五年里，CCH通过儿童研究所和卫生部投资了超过2000万美元来扩大研究。去年，CCH承诺更大幅度地扩大设施和教职员工。因此，我们准备扩大我们成功的CHRCDA计划。我们精心挑选了来自儿童研究所和俄亥俄州立大学的6个系、3个学院和3个学院的21名高级教职员工作为既定的调查人员。此外，我们已为这项续期申请物色了一批优秀的准学者。

DESCRIPTION (provided by applicant): The long-term objective of Columbus Children's Hospital Child Health Research Career Development Award (CCH-CHRCDA) is to train new pediatric physician-scientists. Because of rapid advances in biomedical sciences during the past decade, there is a pressing need to speed the transfer of basic science discoveries to clinical applications that will benefit the health of children. As a large, multidisciplinary Department of Pediatrics (Ohio State University) at a hospital devoted solely to the care of children (CCH), we are ideally positioned to further this cause. We will continue the theme of our existing CHRCDA for this competing renewal application - molecular medicine in pediatrics. Although science and medicine have moved forward at a rapid pace since our original application in 1996, the basic premise of our chosen theme has only gained validation. We are proud of our achievements over the last four years. Our first three CHRCDA Scholars have all in succession obtained independent NIH R01 funding. Including our 3 Scholars currently receiving CHRCDA funding, 50% (3/6) have been women and 17% (1/6) have been minorities (African). Institutional support of research and the CHRCDA has never been stronger. Over the past five years, CCH has invested in excess of $20 M to expand research through Children's Research Institute and the Department. Last year, CCH committed to an even more substantial expansion of facilities and faculty. Thus, we are poised to extend our successful CHRCDA program. We have handpicked 21 senior faculty representing 6 Departments, 3 Colleges, and 3 Institutes across Children's Research Institute and The Ohio State University to serve as Established Investigators. Furthermore, we have identified an outstanding pool of prospective scholars for this renewal application.