CORE--Patient Services Core

患者服务核心为我们的患者、他们的家庭、社区成员、医生和其他卫生专业人员带来了最先进的教育、咨询和诊断服务，因为核心的医生科学家和与波士顿综合镰状细胞中心相关的联合卫生专业人员。通过我们的外展计划，我们使波士顿综合镰状细胞中心的服务提供给不在我们主要教学医院接受初级保健的社区成员。向有镰状细胞病和相关疾病风险的患者和家庭提供专业咨询。我们向卫生专业人员提供有关镰状细胞病和相关疾病的教育。还向有镰状细胞病和相关疾病风险的患者和家庭提供教育。我们

The Patient Service Core brings to our patients, their families, community members, physicians and other health professionals, state-of-the-art educational, counseling, and diagnostic services made available because of the core of physician-scientists and allied health professionals associated with the Boston Comprehensive Sickle Cell Center. Through our outreach programs, we make services of the Boston Comprehensive Sickle Cell Center available to community members not receiving primary care at our major teaching hospitals. Professional counseling is provided to patients and families at risk for sickle cell disease and related disorders. We provide education to health professionals about sickle cell disease and related disorders. Education is also provided to patients and families at risk for sickle cell disease and related disorders. We also have established a hemoglobin diagnosis laboratoryproviding hemoglobinopathy screening using innovative technology and definitive hemoglobin diagnosis by mass spectrometry. A major limitation of HPLC for hemoglobinopathy detection is present during the study of sickle hemoglobinopathies where a clinically important interference exists between HbA2 and an adduct of HbS when using the Bio Rad Variant II method. Capillary zone electrophoresis, an alternative to isoelectric focusing, has found many uses in the research laboratory due to its simplicity, superior resolution, linearity, precision, reproducibility, speed of analysis, and automated operation. Using capillary zone electrophoresis the quantitation of HbA2 is not affected by the presence of HbS and capillary zone electrophoresis can resolve HbA1c from carbamylated HbA1a, A1b, A1d, F, C, and O-Arab. We will explore and develop the use of capillary zone electrophoresis for routine hemoglobinopathy and thalassemia detection.