Training Program in Molecular Medicine

描述(由申请人提供)：这项提案要求资金支持维克森林大学医学院最近建立的一项新颖的培训计划的博士前实习生，该计划授予分子医学博士学位。分子医学计划解决了培养有才华的研究科学家的迫切需求，这些科学家能够从事介于基础和临床调查医学之间的职业生涯。这个分子医学研究生项目有几个鲜明的特点。一个同时拥有医学博士和博士学位的团队为每个受训人员提供正式的指导。学员成为一家新成立的 NIH资助的多学科临床研究计划(PCR)，为分子医学博士计划、面向医生的分子医学硕士计划、面向医生和其他医疗保健专业人员的流行病学和健康服务硕士计划以及医学院的MD/博士计划提供行政支持。在研究生课程的所有受训人员之间进行互补的大学和教育互动。重点放在开展研究/道德、招募少数族裔、学术研究的职业发展和推销方案方面的培训。分子医学博士前课程的其他新特点包括一门涉及受训者与医生和患者直接互动的课程，以及一门高度专业化的人类疾病分子基础教学课程。受训者从事的尖端研究集中在人类遗传学和基因表达，或人类细胞生物学(信号、蛋白质运输、生长和分化以及细胞凋亡)。这些研究 经验可以转化为癌症、传染病和过敏性疾病、心血管疾病、糖尿病、肾脏疾病、疼痛控制和药物滥用的神经科学领域。多学科的教员来自内科、儿科、外科和麻醉科的临床科学系，生物化学、生理学和药理学、微生物学和免疫学、癌症生物学和病理学的基础科学系，以及新成立的人类遗传学中心。这笔培训补助金将允许最具竞争力的申请者和少数族裔继续增长和招募到该计划中。

DESCRIPTION (provided by applicant): This proposal requests funds to support predoctoral trainees in a recently established and novel training program at Wake Forest University School of Medicine, which confers a doctorate in Molecular Medicine. The Molecular Medicine program addresses the critical need for generating talented research scientists who can pursue a career that lies at the interface between basic and clinical investigative medicine. There are several distinctive features of this Molecular Medicine graduate program. A team containing both an M.D. and a Ph.D. provides formalized mentoring for each trainee. Trainees become members of a newly established multidisciplinary NIH funded Program for Clinical Research (PCR), which provides administrative support for the Molecular Medicine Ph.D. program, a Masters in Molecular Medicine program for physicians, a Masters program in Epidemiology and Health Services for physicians and other health care professionals, and the MD/PhD program of the medical school. Complementary collegial and educational interactions occur among all trainees in the graduate programs. An emphasis is placed on training in the conduct of research/ethics, recruitment of minorities, career development in academic research, and marketing the program. Other novel features specific of the Molecular Medicine predoctoral program include a course involving direct interaction of trainees with physicians and patients, and a highly specialized didactic course to Molecular Basis of Human Disease. Trainees perform cutting-edge research that is focused in either human genetics and gene expression, or human cell biology (signaling, protein trafficking, growth and differentiation, and apoptosis). These research experiences translate to the fields of cancer, infectious and allergic diseases, cardiovascular diseases, diabetes, renal diseases, pain control, and the neuroscience of substance abuse. A multidisciplinary faculty comes from the clinical sciences Departments of Internal Medicine, Pediatrics, Surgery, and Anesthesiology, the basic sciences Departments of Biochemistry, Physiology and Pharmacology, Microbiology and Immunology, Cancer Biology, and Pathology, and from the newly established Center for Human Genetics. This training grant will allow continued growth and recruitment of the most competitive applicants and minorities into the Program.