Microarray Core

微阵列核心设施的总体目标是向调查人员提供全面服务 进行大规模的基因组或基因表达谱实验。核心人员提供以下建议 微阵列实验的设计和初始实验的任何后续行动。核心人员流程 使用标准化协议的RNA样本用于基因表达阵列和标准化的DNA样本 单核苷酸多态阵列的方案。在实际实验的每一步，质量控制都是 以确保最终产品是用于提取有用生物信息的有效数据集。堆芯 人员管理从微阵列实验产生的计算机化数据，并维护 本地产生的或通过合作研究获得的微阵列数据的数据库。这些数据是 可通过本地网络以任何标准格式分发用于分析目的、基于Web的 门户或文件传输协议(Ftp)服务器。核心人员协助分析许多 由癌症中心成员进行的实验，并作为相关信息的主要来源 对微阵列结果的后续评估和生物学意义的确定。

The overall objective of the Microarray Core Facility is to provide a comprehensive service to investigators performing large scale genomic or gene expression profiling experiments. Core personnel provide advice on the design of microarray experiments and any follow-up to the initial experiment. Core personnel process RNA samples using standardized protocols for gene expression arrays and DNA samples with standardized protocols for single nucleotide polymorphism arrays. At each step of an actual experiment, quality control is performed to ensure that the final product is a valid dataset for extracting useful biological information. Core personnel manage the computerized data generated from microarray experiments and maintain the database of microarray data generated locally or obtained through collaborative research. The data are available for distribution for analysis purposes, in any standard format through local networks, a web-based portal, or a File Transfer Protocol (ftp) server. Core personnel assist in the analysis of many of the experiments performed by Cancer Center members and serve as the primary source of information related to the follow-up evaluation of the microarray results and identification of biological implications.