Analytic Microscopy

分析显微镜核心设备(AMC)成立于1999年，作为一个集中共享的 提供光学显微镜应用方面的科学和技术专业知识的资源。AMC是一种 癌症中心研究人员对细胞内转运和亚细胞运输感兴趣的宝贵资源 涉及蛋白质磷酸化、信号转导、细胞周期进程、细胞转导的分子定位 细胞接触，细胞运动，细胞分化，细胞凋亡，血管生成，侵袭或转移，DNA修复， 基因表达和药物发现。AMC的主要目标是为癌症中心的研究人员提供 使用最新的光学显微镜成像系统，包括：宽场荧光和共焦 显微镜；图像分析和激光捕获显微解剖。 在过去的五年中，AMC机构为癌症科学做出了积极的贡献 中心。自2000年以来，在AMC融资机制的支持下，出版了近100份出版物。AMC CORE增加了新的最先进的仪器设备，从而使CORE设施的使用率稳步上升 癌症中心的调查人员。 AMC融资机制的未来计划是最大限度地发挥现有文书的潜力，并进一步 开发先进的显微镜应用程序。为了实现这些目标，AMC基金将实施一系列 采取主动行动，教育和培训内部和外部资助的调查人员使用先进的 显微镜和成像技术。此外，核心将侧重于便利调查人员 认识和获得共焦显微镜和荧光显微镜。为此，AMC基金将提供 在这些领域举办了一系列普通显微镜讲习班，以帮助增长知识和技能基础 该设施的用户。

The Analytic Microscopy Core Facility (AMC) was established in 1999 to serve as a centralized shared resource that provides scientific and technical expertise in optical microscopy applications. The AMC is an invaluable resource for Cancer Center researchers interested in intracellular trafficking and sub-cellular localization of molecules involved in protein phosphorylation, signal transduction, cell cycle progression, cellto- cell contact, cell motility, cell differentiation, apoptosis, angiogenesis, invasion or metastasis, DNA repair, and gene expression and drug discovery. The AMC's primary goal is to provide Cancer Center investigators with access to the latest optical microscopy imaging systems, including: widefield fluorescence and confocal microscopy; image analysis and laser capture microdissection. In the last five years the AMC Facility has actively contributed significantly to the science of the Cancer Center. Work supported by the AMC Facility has resulted in nearly 100 publications since 2000. The AMC Core has added new state-of-art instrumentation resulting in a steady rise in usage of the Core Facility by the Cancer Center investigators. The future plans of the AMC Facility are to maximize the potential of the current instruments and further develop advanced microscopy applications. To achieve these goals the AMC Facility will implement a series of initiatives to educate and train intra- and extramurally-funded investigators in the use of advanced microscopy and imaging techniques. In addition the Core will focus on facilitating the investigators awareness and access to confocal and fluorescence microscopy. To this end the AMC Facility will offer a series of general microscopy workshops in these areas, to assist in growing the knowledge and skill base of the facility's users.