ORGANIZATION OF KEYSTONE CONFERENCE ON PROTEOMICS AND BIOINFORMATICS, APRIL 2005

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。教授。2005年4月8日至13日，Costello和Mann组织了蛋白质组学和生物信息学的基石研讨会（X3），与系统和生物学的基石研讨会（X4）同时举行。她在一次联合会议上发表了关于糖蛋白组学的特邀演讲，并与人合著了几张海报。一个由近400人组成的非常国际化的团体出席了联席会议，并对会议表示高度热情。蛋白质组学和生物信息学会议通过S13拨款获得了美国国立卫生研究院的资助。该提案的摘要如下：蛋白质组学已成为后基因组学的一门关键学科。工具箱?在过去的几年里，蛋白质组学技术已经变得非常强大。质谱法、基于阵列的蛋白质方法和单细胞成像方法相结合，为我们提供了细胞中所有表达蛋白质的丰富数据。其蛋白质组?。虽然这项技术仍在迅速发展，而且？数据收集?这次会议的重点将是蛋白质组学在分子细胞生物学和分子医学中解决问题的应用。生物信息学方法跟踪数据的财富和开始努力整合不同的大规模数据集也将被强调。生物信息学和系统生物学的另一个新兴领域是全细胞模型的建立。蛋白质组学的快速发展，目前迫切需要制定实验方法和数据解释的标准和协议，以及具有不同背景（如生物学，医学，生物化学，生物信息学）的研究人员之间方便沟通的必要性，工具)使得Keystone格式非常适合在有足够机会在小组内和个人之间进行讨论的环境中及时交换信息。学生和博士后将能够展示他们的工作，并与领先的研究人员建立联系，从而增加他们自己的曝光率，并建立联系，从而在快速发展的领域创造就业机会，这些领域对训练有素、富有创造力的研究人员有很高的需求。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Profs. Costello and Mann organized the Keystone Symposium on Proteomics and Bioinformatics (X3), held simultaneously with the Keystone Symposium on Systems and Biology (X4) Keystone, CO, April 8-13, 2005. She presented an invited lecture on Glycoproteomics to a joint session and was coauthor of several posters. A very international group of almost 400 persons attended the joint meetings and expressed high enthusiasm for them. The Proteomics and Bioinformatics meeting obtained funding from NIH through a S13 grant. The abstract for the proposal read as follows: Proteomics has emerged as a key discipline in the post-genomic ?tool chest? and over the last few years, proteomics technology has become extraordinarily powerful. Mass spectrometry, array based protein methods and single cell imaging methods have combined to give us rich data of all the expressed proteins of the cell, ?its proteome?. While the technology is still developing rapidly, and ?data collection? efforts are just gathering steam, the focus of this meeting will be on applications of proteomics to problem solving in molecular cell biology as well as in molecular medicine. Bioinformatics methods to keep track of the wealth of data and beginning efforts to integrate disparate large-scale data sets will also be highlighted. Another emerging area in bioinformatics and systems biology is the building of models of whole cells. The rapid growth of proteomics, the present pressing need for the development of standards and protocols for the experimental methods and data interpretation, and the necessity for facile communication among investigators having disparate backgrounds (e.g., biology, medicine, biochemistry, bioinformatics, instrumentation) makes the Keystone format ideal for the timely exchange of information in a setting where there is ample opportunity for discussions within small groups and between individuals. Students and postdoctoral fellows will be able to present their work and to make connections with leading investigators, thus increasing their own exposure and forging connections that can generate career opportunities in rapidly expanding fields where there is high demand for well-trained, creative researchers.