THE EFFECT OF AEROBIC EXERCISE ON BLOOD PRESSURE AMONG AFRICAN-AMERICAN WOMEN

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这将是一项在130名患有高血压（收缩压/舒张压[B/P]大于或等于140/90 mmHg或正在服用降压药物）的非洲裔美国女性中进行的多中心、平行组、随机对照试验。 这项随机对照试验的主要目的是确定12周有氧运动对已确诊高血压的非裔美国妇女的降压效果。本研究的第二个目的是测试12周的有氧运动是否可以改善患有高血压的非洲裔美国女性的以下心血管疾病风险因素：总胆固醇，甘油三酯，脂蛋白（HDL和LDL）水平，血糖和胰岛素。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This will be a multi-center, parallel arm, randomized controlled trial among 130 African-American women with hypertension (systolic/diastolic blood pressure [B/P] greater then or equal to 140/90mmHg or currently taking anti-hypertensive medications). The primary aim of the proposed randomized, controlled trial is to determine the BP lowering effect of 12 weeks of aerobic exercise among African-American women with established hypertension. The secondary aim of this study is to test whether 12 weeks of aerobic exercise improves the levels of the following cardiovascular disease risk factors among African-American women with hypertension: total cholesterol, triglycerides, lipoprotein (HDL and LDL) levels, serum glucose and insulin.