Conference on the Integrative Biology of Exercise

描述（由申请人提供）：本提案的目的是为计划于2008年9月24日至27日在南卡罗来纳州希尔顿黑德举行的“运动综合生物学”APS会议寻求支持。本次会议旨在汇集来自世界各地的科学家，他们已经参与研究或对运动生理学的广泛领域有研究兴趣。这是美国生理学会（American Physiological Society）每四年举办一次的系列会议中的第五次。科学项目的组织基于两个特点，这两个特点在以前的会议上被证明是非常成功的：1)一个强有力的科学项目与参与者的互动，2)强调年轻研究者进行的新兴研究。该计划侧重于自四年前的上次会议以来发展的新见解，重点关注传统运动领域的最新重要进展（例如，代谢控制，细胞信号传导，卫星/干细胞生物学，肥大，血管适应）以及新兴科学领域的重大新发展，这些领域与对运动感兴趣的研究者有很大的相关性（例如，机械信号转导，AMPK，细胞因子）。我们继续关注这一重点，但并非没有纳入其他重要的研究方面，对锻炼社区的浓厚兴趣。此外，有前途的年轻研究人员的参与创造了一个热烈的论坛，庆祝新兴科学家的创造力和活力。会议的基本目标是提供对运动生理学和跨学科努力的深入了解，以评估其对身体系统的影响。该提案的具体目标包括：1)召集一个国际公认的跨学科研究小组参加APS会议，重点研究使用包括生理学、分子生物学和遗传学在内的综合方法研究运动；2)通过设立旅行奖励计划，促进青年科学家广泛参与本次会议，重点是妇女和代表性不足的少数群体；3)使新的研究者和学生有兴趣追求研究机会，了解运动的综合生物学及其与性别和衰老的关系。该项目旨在汇集来自世界各地的科学家，他们已经参与研究或对运动生理学的广泛领域有研究兴趣。科学计划的目的是提供一个强有力的科学计划与参与者的互动，并强调新兴的研究由年轻的研究者进行。与会者可能会关注传统运动领域的最新重要进展（例如，代谢控制、细胞信号传导、卫星/干细胞生物学、肥大、血管适应），以及与运动研究人员感兴趣的新兴科学领域的重大新发展（例如，机械信号转导、AMPK、细胞因子）。目标是提供对运动生理学和跨学科努力的深入了解，以评估其对身体系统的影响。此外，目标是概述未来工作的方向，并吸引新的研究者和学生追求研究机会，以了解运动的综合生物学及其与性别和衰老的关系。

DESCRIPTION (provided by applicant): The purpose of this proposal is to seek support for an APS Conference on the "Integrative Biology of Exercise V," scheduled for September 24-27, 2008 in Hilton Head, South Carolina. This Conference is designed to bring together scientists from all over the world who have been involved in research or have research interest in the broad area of exercise physiology. It represents the fifth in a series of meetings that have been sponsored by the American Physiological Society every four years. The scientific program has been organized based upon two features that have proven extremely successful in previous meetings: 1) a strong scientific program with participant interaction, and 2) an emphasis on emerging research performed by young investigators. The program focuses on new insights developed since the previous meeting four years ago, focusing on recent important advancements in the traditional areas of interest in exercise (e.g., metabolic control, cell signaling; satellite/stem cells biology; hypertrophy; vascular adaptations) as well as on significant new developments in emerging areas of science that have great relevance to investigators interested in exercise (e.g., mechanical signal transduction; AMPK; cytokines). We continue this focus, but not without inclusion of other important research aspects of keen interest to the exercise community. In addition, involvement of promising young investigators has created an enthusiastic forum for celebrating the creativity and energy of emerging scientists. The fundamental goal of the Conference is to provide an in- depth understanding of exercise physiology and interdisciplinary efforts to assess its impact on the systems of the body. The specific aims of this proposal include: 1) to convene an internationally recognized and interdisciplinary group of investigators to an APS Conference focusing on the use of integrative approaches for the study of exercise involving physiology, molecular biology, and genetics; 2) to promote the wide-spread participation of young scientists in this Conference, with an emphasis on women and underrepresented minorities, through the establishment of a travel award program; and 3) to interest new investigators and students in pursuing research opportunities to understand the integrative biology of exercise and its relation to gender and aging. This project is designed to bring together scientists from all over the world who have been involved in research or have research interest in the broad area of exercise physiology. The scientific program is designed to provide a strong scientific program with participant interaction and emphasize emerging research performed by young investigators. The participants will likely focus on recent important advancements in the traditional areas of interest in exercise (e.g., metabolic control, cell signaling; satellite/stem cells biology; hypertrophy; vascular adaptations) as well as on significant new developments in emerging areas of science that have great relevance to investigators interested in exercise (e.g., mechanical signal transduction; AMPK; cytokines). The goal is to provide an in-depth understanding of exercise physiology and interdisciplinary efforts to assess its impact on the systems of the body. In addition, the goal is to outline directions for future work and to interest new investigators and students in pursuing research opportunities to understand the integrative biology of exercise and its relation to gender and aging.