Training Program in Molecular Medicine

描述（由申请人提供）：该提案要求提供资金，以支持维克森林大学医学院最近建立的新培训计划中的博士前学员，该计划授予分子医学博士学位。 分子医学计划解决了培养有才华的研究科学家的迫切需要，他们可以从事基础和临床研究医学之间的职业。 有这个分子医学研究生课程的几个显着特点。 一个既有医学博士和博士为每一位受训者提供正式的指导。 学员成为新成立的 多学科NIH资助的临床研究计划（PCR），为分子医学博士提供行政支持。该计划，在分子医学硕士课程的医生，在流行病学和卫生服务硕士课程的医生和其他医疗保健专业人员，以及医学院的MD/博士课程。 互补的学院和教育互动发生在研究生课程的所有学员之间。 重点放在研究/道德行为的培训，少数民族的招聘，学术研究的职业发展和营销方案。 分子医学博士前课程的其他新特点包括涉及受训人员与医生和患者直接互动的课程，以及人类疾病分子基础的高度专业化的教学课程。 学员进行前沿研究，重点是人类遗传学和基因表达，或人类细胞生物学（信号传导，蛋白质运输，生长和分化，凋亡）。 这些研究 经验转化为癌症、传染病和过敏性疾病、心血管疾病、糖尿病、肾病、疼痛控制和药物滥用的神经科学领域。 多学科的教师来自内科，儿科，外科和麻醉学的临床科学部门，生物化学，生理学和药理学，微生物学和免疫学，癌症生物学和病理学的基础科学部门，以及新成立的人类遗传学中心。 该培训补助金将允许最具竞争力的申请人和少数民族进入该计划的持续增长和招聘。

DESCRIPTION (provided by applicant): This proposal requests funds to support predoctoral trainees in a recently established and novel training program at Wake Forest University School of Medicine, which confers a doctorate in Molecular Medicine. The Molecular Medicine program addresses the critical need for generating talented research scientists who can pursue a career that lies at the interface between basic and clinical investigative medicine. There are several distinctive features of this Molecular Medicine graduate program. A team containing both an M.D. and a Ph.D. provides formalized mentoring for each trainee. Trainees become members of a newly established multidisciplinary NIH funded Program for Clinical Research (PCR), which provides administrative support for the Molecular Medicine Ph.D. program, a Masters in Molecular Medicine program for physicians, a Masters program in Epidemiology and Health Services for physicians and other health care professionals, and the MD/PhD program of the medical school. Complementary collegial and educational interactions occur among all trainees in the graduate programs. An emphasis is placed on training in the conduct of research/ethics, recruitment of minorities, career development in academic research, and marketing the program. Other novel features specific of the Molecular Medicine predoctoral program include a course involving direct interaction of trainees with physicians and patients, and a highly specialized didactic course to Molecular Basis of Human Disease. Trainees perform cutting-edge research that is focused in either human genetics and gene expression, or human cell biology (signaling, protein trafficking, growth and differentiation, and apoptosis). These research experiences translate to the fields of cancer, infectious and allergic diseases, cardiovascular diseases, diabetes, renal diseases, pain control, and the neuroscience of substance abuse. A multidisciplinary faculty comes from the clinical sciences Departments of Internal Medicine, Pediatrics, Surgery, and Anesthesiology, the basic sciences Departments of Biochemistry, Physiology and Pharmacology, Microbiology and Immunology, Cancer Biology, and Pathology, and from the newly established Center for Human Genetics. This training grant will allow continued growth and recruitment of the most competitive applicants and minorities into the Program.