Immersion in Drug Abuse

NIDA进行的一项全国性调查报告说，在美国分娩的400万妇女中， 1992年，她在怀孕期间服用了非法药物。除了心理社会影响外，非法药物 使用还对胎儿和新生儿的神经系统发育具有不利影响， 增加了青少年冒险行为的可能性。对这种生物学知之甚少， 在发育中的胎儿和新生儿中对非法药物成瘾，很少有研究人员专门研究这一重要问题。 领域为了响应该计划公告（PAR-04-054），药物滥用研究教育赠款 和成瘾，这项建议的总体目标是汇集科学和教育 约翰霍普金斯和摩根州立大学的药物滥用研究专家， 教育/研究培训计划，其使命是培训基础生物学研究人员 和心理社会方面的问题， 孕妇和她的胎儿及新生儿。在埃斯特尔·高达医学博士的共同指导下，一 约翰霍普金斯大学的科学家兼医生，以及加布丽尔·麦克莱莫尔博士，摩根州立大学的教育家兼科学家 大学，我们已经建立了一个伙伴关系，调查人员从中心成瘾和 怀孕在约翰霍普金斯湾景医疗中心，肯尼迪克里格家庭中心，该部门 约翰霍普金斯大学和摩根州立大学的儿科和青少年医学， 通过2个教育计划实现这一目标。夏季沉浸在药物滥用研究中 计划（SIDARP）是一个为期10周的教育研究/培训经验，将针对博士 学生，医学生和医生在他们的职业生涯的早期阶段。药物滥用 研究培训（DART）计划是一个长期（2-3年）的研究经验，旨在针对预 博士后和临床科学家成为药物领域的下一代领导者 成瘾和滥用研究和教育。培训计划将使用基于能力的学习 最大化学习的策略。重点将是提供教育和研究机会， 将包括调解胎儿和新生儿的药物依赖和耐受性的基本机制， 阿片类药物暴露对人类胎儿行为和新生儿大脑发育的影响，替代治疗和 怀孕期间和新生儿中阿片剂成瘾的解毒战略以及药物滥用 对育龄妇女的干预和预防战略。

A NIDA conducted national survey reported that 5.5% of 4 million women who gave birth in the United States in 1992 used illegal drugs while they were pregnant. In addition to the psychosocial ramifications, illicit drug use also has adverse effects on the development of the nervous system in the fetus and newborn and increases the possibilities of risk taking behavior in adolescence. Little is known about the biology of addiction to illicit drugs in the developing fetus and newborn and few investigators specialize in this important field. In response to the program announcement (PAR-04-054), Research Education Grants in Drug Abuse and Addiction, the overall goal of this proposal is to bring together the scientific and educational expertise in drug abuse research at Johns Hopkins and Morgan State University to create a novel educational/research training program with the mission of training researchers in the basic biology and psychosocial aspects of illicit drug use in the young woman entering reproductive age, the pregnant woman, and her fetus and newborn. Under the co-directorship of Estelle Gauda, M.D., a physician-scientist at Johns Hopkins, and Gabrielle McLemore, Ph.D., a educator-scientist at Morgan State University, we have created a partnership between investigators from the Center for Addiction and Pregnancy at Johns Hopkins Bayview Medical Center, the Kennedy Krieger Family Center, the Department of Pediatrics and Adolescent Medicine at Johns Hopkins University, and Morgan State University to accomplish this goal through 2 educational programs. The Summer Immersion in Drug Abuse Research Program (SIDARP) is a 10 week educational-research/training experience which will target doctoral students, medical students, and physicians at an early stage of their professional careers. The Drug Abuse Research Training (DART) Program is a long-term (2-3 years) research experience designed to target pre and postdoctoral students and clinician-scientists to be the next generation of leaders in the field of drug addiction and abuse research and education. The training program will use a competency based learning strategy to maximize learning. Emphasis will be given to having educational and research opportunities that will include basic mechanisms mediating drug dependence and tolerance in the fetus and newborn, effects of opiate exposure on human fetal behavior and newborn brain development, alternative treatment and detoxification strategies for opiate addiction during pregnancy and in the newborn, and drug abuse intervention and prevention strategies in women of reproductive age.