SNP Confirmation and High Throughput Genotyping Core

SNP确认和高通量基因分型中组装的能力 核心(SNP-Gen核心)为中心调查人员(和更大的机构)提供单点 实验技术方面的综合建议(辅导) 操纵核酸，获得训练有素的技术人员和非常 精密而昂贵的设备。对于大多数人来说，Core将提供分析开发， 数据收集，或核苷酸合成。在某些情况下，建议和教育将是 获得。此核心集中了高效和 可靠地产生高质量的核酸分析数据。通过本网站提供的服务 核心包括DNA测序、单核苷酸多态(SNP)基因分型、 插入/缺失分析、串联重复基因分型、小鼠和 MAN和SNP数组。有适当的内部质量控制制衡机制 并在修订后的申请中概述。与每个中心的互动 调查人员将进行量身定做，以满足每个人的个别培训需求。其核心是 用于高效、经济地提供数据和服务。在某些情况下 将产生海量的高吞吐量数据。

The capabilities assembled in the SNP Confirmation and High Throughput Genotyping Core (SNP-Gen Core) provide the Center Investigators (and larger institution) a single point of entry, comprehensive advice (mentoring) for the technical aspects of experiments manipulating nucleic acids, access to highly-trained technical personnel and very sophisticated and expensive equipment. For most, the Core will offer assay development, data collection, or nucleotide synthesis. In some situations advice and education will be obtained. This Core centralizes the equipment and experience needed to efficiently and reliably produce high quality nucleic acid analysis data. The services available through this Core include DMA sequencing, single nucleotide polymorphism (SNP) genotyping, insertion/deletion analysis, tandem repeat genotyping, expression arrays in mouse and man, and SNP arrays. Appropriate internal quality control checks and balances are in place and are outlined in the revised application. The interaction with each of the Center Investigators will be tailored so that the individual training needs of each are met. The core serves to provide data and services efficiently and economically. In some situations massive high throughput data will be generated.