CTSA INFRASTRUCTURE FOR CLINICAL TRIALS

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 耶鲁大学临床研究中心（YCCI）的成立是为了提供一个“家”，培养下一代的临床研究人员。主要计划目标是1）吸引医学，护理，公共卫生，生物科学和生物医学工程方面的高素质学生和初级教师;并培训他们使用最先进的研究工具;让他们掌握在复杂研究中工作的技能。 团队; 2）通过以下方式促进将与疾病相关的发现从实验室转化为社区：鼓励创建跨学科团队;提供最先进的核心设施和扩大的生物统计和生物信息学资源;建立临床研究的组织和监管基础设施;并建立一个充满活力的新伙伴关系，将社区领导人，医生和健康中心整合在一起。参与机构包括医学院、护理学院、公共卫生学院、生物医学工程系以及生物和生物医学科学研究生课程。研究性医学计划（IMP） YCCI的教育和培训工作的核心。这是一个独特的博士课程，提供博士学位。从健康科学研究到高质量医学博士从事转化或临床研究的研究员。在CTSA的支持下，IMP将扩大到包括护理，公共卫生，生物科学和MD-PhD学生。YCCI还创建了一个YCCI教师导师协会，他们将积极参与培训和培养被确定为YCCI临床学者的学生和初级教师。试点和可行性（P&F）赠款将被授予。1)初级教师; 2）跨学科翻译团队; 3）新技术;和4）基于社区的项目。YCCI将集群研究 核心围绕共同的主题，包括：成像;标本分析;生理学;认知和行为;药物开发;和细胞治疗。一个新的研究服务办公室将为“一站式”采购管理、生物统计、生物信息学、征聘和其他支助服务提供便利。YCCI将有 一个办公室，以协调大学的努力，以解决我们社区面临的健康问题。该大学的决定，立即提供实质性的支持，以建立YCCI反映了其坚定的承诺，以创新的重新设计我们的临床和转化研究活动

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Yale Center for Clinical Investigation (YCCI) was created to provide a "home" for training the next generation of clinical investigators. Key programmatic goals are to 1) attract highjy talented students and junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering; and train them in the use of state-of-the-art research tools; give them the skills to work within complex research teams; and support their professional development; and 2) foster the translation of disease-related discoveries from the laboratory into the community by: stimulating the creation of Interdisciplinary teams; making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources; establishing organizational and regulatory infrastructure for clinical studies; and forging a dynamic new partnership that will integrate community leaders, physicians, and health centers. Participating institutions include the Schools of Medicine, Nursing, Public Health, the Department of Biomedical Engineering and Graduate Programs in Biological and Biomedical Sciences. The Investigative Medicine program (IMP) is central to YCCI's education and training efforts. It is a unique doctoral program that offers Ph.D. degrees in Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical research. IMP will be expanded with CTSA support to include nursing, public health, biological sciences, and MD-PhD students. YCCI has also created a Society of YCCI Faculty Mentors who will participate actively in the training and nurturing of the students and junior faculty members identified as YCCI Clinical Scholars. Pilot and feasibility (P&F) grants will be awarded for. 1) junior faculty; 2) interdisciplinary translational teams; 3) new technologies; and 4) community-based projects. YCCI will cluster research cores around common themes, including: imaging; specimen analysis; physiology; cognition and behavior; drug development; and cell therapy. A new Office of Research Services will provide facilities for "one-stop" shopping for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have an office to coordinate the University's efforts to address health issues facing our community. The University's decision to immediately provide substantial support to establish the YCCI reflects its strong commitment to an innovative redesign of our clinical and translational research activities